Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09645 Pf-431396 GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 71 KLF6; PBXIP1; RHOA; TDRD3; NCOA2; PSPC1; DNAJC1; KLF5; TCEA2; BAZ2A; CARHSP1; SOX4; MLLT10; ZNF165; SAP18; MED15; IFI16; TXNIP; EHMT2; PAX8; ZSCAN31; MYCL; ZNF219; FOXN3; ETS2; TCF20; ATF7IP; PBX1; TRIM29; NR1H3; AES; SMARCA2; BAZ2B; HTATIP2; FOXJ3; BMI1; ID1; GRHL2; INSR; BRD2; BCL11A; TBX2; ID4; RLF; JUP; ZSCAN18; HMGA1; DACH1; TBX3; HOXB7; DNMT3B; ZMYND8; PPARG; ZNF160; ZNF721; MECOM; ZBTB20; TSC22D1; HOXC10; OSR2; KLF4; INSM1; TLE4; ELF3; RBPMS; TOX3; TFAP2C; ESR1; SATB1; MEIS1; ABL1
Down-regulation 42 LOXL2; BIRC2; KLF7; TLE1; XBP1; RUVBL1; ZSCAN32; ZNF189; ETV5; ACTL6A; BCL10; CCDC59; MLX; FOSL1; MYNN; NKRF; FOXD1; TRIM32; ZNF512B; RNF111; EGR3; RUVBL2; ZBTB18; TBL1X; CCNC; BRD3; DEK; ZMIZ1; APEX1; ELK3; NR4A2; ZNF532; FOXG1; TAL1; ZIC1; MAFB; ERBB4; NKX3-1; EGR2; LEF1; KDM5D; GATA2