Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09641 Gsk-1059615 GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 85 HDAC6; FOXO4; KLF11; LMCD1; BACH1; JUP; SOX4; SAFB; TXNIP; SMAD4; NFYC; HDAC5; ZNF529; PPP1R13L; HIVEP1; TCF7L2; ZBED1; ZNF711; CALCOCO1; BRWD1; TCEA2; EZH1; HEY2; ZNF14; CBX5; PHIP; FOXN3; ZNF571; NEUROD1; NR4A3; NFYB; ZNF184; PAWR; HMGB3; CBFA2T3; MED14; MED23; ZNF304; TGFB1I1; ELF2; ZNF268; TGIF1; HDAC7; TRAK1; MAFF; BRD8; ZNF117; WNT4; HSBP1; ZNF232; INSR; JARID2; HBP1; CHD9; E2F8; RCOR1; ZNF281; TAF1D; JUND; CITED2; ARID5B; YBX3; KDM5D; PBX1; ELF3; FLNA; HIC2; OSR2; TRIM22; NR4A2; IRF7; NKX2-2; PHF20; ID3; NR5A2; GATA6; AEBP1; ZNF532; NKX3-1; HIRA; ERBB4; TSC22D1; TOX; PSIP1; ABL1
Down-regulation 25 HOXA5; NFIL3; PAX8; MTDH; NRIP1; HOXB2; HOXB5; RAN; HOXB6; ATF5; MBD2; HEY1; ZIC1; BCL11B; TBX3; LITAF; TP63; MAFB; BTG1; HOXB7; KLF5; SATB1; GATA2; TBX2; PPARG