Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09640 Gsk-1059615 GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 90 MNAT1; FOXO4; HDAC6; SOX4; TCEA2; HDAC5; MZF1; HOXA5; FOXN3; INSR; PPARD; CALCOCO1; TCF4; CNOT2; BAZ2B; ZNF227; BRD8; BRWD1; ZNF500; NR4A1; CBX7; PCGF3; THAP10; PBXIP1; JUP; DEK; PBX1; HBP1; TULP3; ZNF112; ZNF573; PPP1R13L; ST18; MED23; NR2C1; PNRC1; CREBL2; CBFA2T3; BACH1; ZNF337; ZNF544; ZFPM2; TGFB1I1; KLF11; PRRX1; ZNF532; PAX6; ZEB1; TRIM22; ZNF665; ZNF281; NEUROD1; ERG; ZBED1; YBX3; NCOR2; E2F8; ZNF83; ETV5; CENPF; CUX1; TCEB2; DLX5; TOB1; BCL11A; UBE2B; FOXA2; TERF1; HLX; TGFB1; KLF2; SMAD1; TWIST1; AEBP1; CEBPB; ZBTB16; MECOM; ZNF721; ZSCAN18; ZNF160; IFI16; ZNF423; TGIF1; MYBL1; FOSB; MEIS2; OSR2; TSC22D1; NR4A2; ESR1
Down-regulation 57 PUF60; HMG20B; NFKBIA; PAX8; TFDP1; NFIL3; BASP1; NFKB1; MTDH; FOSL1; MBD2; HOXC10; BHLHE41; GATAD2A; ENO1; BHLHE40; TEAD1; PIAS2; C1QBP; SMAD2; SOX9; SMARCA5; HOXA10; SOX10; TFAM; WWC1; BMI1; PTRF; NFATC3; ELF5; TCF21; FOXC1; CHD7; RYBP; BBX; YWHAB; ID4; ERBB2; CEBPG; IRF4; TRIM29; HOXB7; SAP30; CITED1; DACH1; SATB2; FOXF1; HOXB6; ABL1; LITAF; HOXB2; PIR; PBX3; SATB1; POU2AF1; PPARG; GATA2