Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09638 Gsk-1059615 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 255 EGR1; JUP; EZH1; ZXDC; FOXO4; MZF1; MTA1; DDIT3; ZNF195; ZNF500; ZNF232; CNOT2; SETDB1; HDAC5; CEBPD; MNT; TCEA2; ING4; ZNF274; TRIB3; KLF13; SOX4; MED12; ZNF688; ZNF446; ARID3B; E4F1; PPP1R13L; NFE2L2; CBFA2T2; HOXD1; CRTC1; PRDM14; ZNF532; TDP2; ZNF154; LZTR1; ZNF282; KLF11; TAF1C; ZFHX3; NR2E1; ZNF264; SPDEF; CTCF; ZNF324; ZNF219; PIAS4; ZNF212; EN1; OVOL2; FOXF2; ZNF180; HBP1; TCF7L2; ZNF211; ZNF235; LHX3; FOXJ1; PCGF3; HDAC4; RUNX3; KLF3; CBX5; SAFB; MEF2C; ZBTB17; PAXBP1; HSF4; HEYL; ZBTB7A; CAMTA2; POU2F1; MAFG; ZSCAN32; HINFP; INSR; PBX1; HDAC9; TFAP4; ZNF33B; ZNF74; HOXB1; ARNT2; TP63; HIVEP3; HSF1; ZNF268; ZNF510; SRCAP; PMS1; ZNF611; SOX9; LHX2; ZNF3; ZNF45; CALCOCO1; HR; YEATS2; TCF25; PRDM2; PAX6; ATF4; THRB; FOXG1; TFAP2A; ZNF117; PRDM10; ZNF544; ZNF43; THAP7; HIC2; MAML1; TERF2; DLX5; ST18; TAF6L; PCGF1; ZNF354A; PHIP; BRWD1; HMGXB4; KLF7; ZNF83; CHD2; ZNF84; NFATC4; MYRF; TGIF1; ZNF671; ZNF345; ZNF562; ZNF415; NFIC; ZNF623; PIAS1; USP21; ZNF816; HEY2; ZNF24; FEZF2; LDB1; ZNF667; INSM1; ZNF273; KLF15; NCOA6; ZNF467; CEBPG; ZNF44; VPS72; HNF4G; MDM2; HOXB5; BARX1; EP300; ZNF184; ZNF224; NEUROG1; ZNF573; NKX3-2; CDIP1; SP2; PRDM1; KDM4C; ZNF304; CBX7; HDAC7; TCEA1; BCL11A; RARG; CAMTA1; NHLH1; RXRA; MED14; HMGA1; ZNF665; PHF20; TULP3; ZNF606; THRA; SREBF1; HIPK2; ATN1; RBFOX2; NCOA2; ZNF423; PHOX2B; NFATC1; TOB1; ZNF432; ZNF536; YBX3; ZNF160; BPTF; BRD4; TCF7; ZNF91; IRF6; BNC1; CREM; UBE2B; MNDA; MED23; SSBP3; CEBPB; SIX3; LHX6; ZNF93; SALL2; NCOA3; JUND; RAD21; ELF4; MEIS2; TSC22D3; TBL1X; TERF1; JUN; BRD2; TRPS1; ID1; IRF8; STAT4; PAX5; HMBOX1; SHOX2; APEX1; OSR2; RORA; TLE2; ZBED1; NEUROD1; PLAGL1; HHEX; HIRA; SOX17; EYA1; NR1H2; ERBB4; TOX; NR4A2; ZBTB16; AHR; ZEB1; KDM5D; HOXB2; FOXF1; ZNF331; TRIM29; PEG3; HES1; SOX11; POU2AF1; ABL1
Down-regulation 85 CCNA2; NFKBIA; MYCBP; NFIL3; FHL2; LOXL2; PAX8; ATF6; XBP1; GTF2A2; DRAP1; MNAT1; TEAD1; ECD; RUVBL1; MTDH; SMAD3; NEDD8; BHLHE40; SFPQ; ATF5; STAT5B; FOSL2; ING2; EED; MED6; REST; NCOA4; MITF; MBD2; PIAS2; PITX2; NPM1; STAT1; LEF1; STAT3; SUMO1; SOX10; CCNC; NR2F2; HOXC6; CREB3L2; ANKRD1; MAX; TBPL1; LMCD1; DNMT3B; ENO1; CTR9; ID2; SIM2; EDF1; MAGED1; TRIM16; ZMYM2; CRY1; HMGN3; WWC1; ZBTB18; BAZ1A; CBFB; NKX3-1; HLTF; PTRF; TAF10; WT1; BIRC2; UBE2I; ZBTB38; CHD7; BMI1; HOXC10; SIX1; PTTG1; NRIP1; DLX2; ELF5; IFI16; ID4; BHLHE41; MYBL1; SATB1; PPARG; NR3C1; TBX2