Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09636 Barasertib-hqpa GSE70138 HA1E Human 24h 0.12uM EID0003
Types Number Response transcription factors
Up-regulation 64 NKX2-2; NR4A3; ADNP; IFI16; NR4A2; CTR9; TOX3; BCL11B; SSX1; INSM1; NCOA2; TGS1; SALL2; ZBED2; ID4; TULP4; GATA6; AFF1; CHD7; CREM; BAZ2B; HES1; PBX2; KMT2A; NR0B1; NFE2L3; ZFHX4; CIZ1; TGIF1; ZFPM2; ZBTB20; PBX1; PRKDC; RNF141; HDAC4; MYB; MYRF; SATB2; HMGB2; LMCD1; EGR2; PITX1; HTATIP2; BMI1; SAP30; TERF1; CERS6; PPARG; ZNF91; CEBPB; ELF3; ZNF331; STAT4; ZHX2; WT1; ST18; TRIP6; PEG3; MNDA; HOXC6; ZEB1; ID1; SATB1; ABL1
Down-regulation 37 LOXL2; NFE2L1; RBBP7; YEATS2; FOXD1; ENO1; HIVEP2; SERTAD2; TOB1; CENPF; HEY1; HOXB6; SIAH2; MECOM; SALL1; MSX1; PIR; TBL1X; ZFP36L1; SOX17; TSC22D1; BRD2; PDLIM1; JUP; KDM5D; DLX5; ELF5; EYA1; HDAC9; ZBED1; EYA2; KLF10; HOXB2; WWTR1; EMX2; GATA2; TBX2