Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09635 Barasertib-hqpa GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 61 KDM5C; TBL1XR1; MXD1; HDAC3; SSBP2; CBFA2T3; HMG20A; DNMT3B; ZNF510; LPIN2; CHD1; MYT1L; HMGB3; CREBZF; SMAD3; CRYM; PGR; MEN1; CHD7; IRX5; MXD4; RAD21; HOXA1; TOPORS; ADRB2; ID4; SERTAD2; ZBTB20; MEF2A; ENO1; DEAF1; RBL2; TCF4; ZNF226; PURA; ETS2; SOHLH2; EMX2; NR1I2; ZNF329; STAT3; BRD3; NKX2-1; NFE2; TGIF1; HOXB13; TFDP2; MEOX2; RXRA; MXI1; SOX17; TLE4; TXNIP; PPARG; KLF9; ZSCAN18; LITAF; DACH1; PBX3; ESR1; SATB1
Down-regulation 77 CRK; RFX5; NR2F2; TCEA2; ZNF91; TGFB1I1; PBX1; ATF4; NRIP1; MNT; NFIB; TEAD4; HHEX; HLF; CSDE1; POLR3C; BCL10; ZNF528; ZNF430; PCGF2; GLI3; TTF2; COPS2; ISL1; ZNF93; DDIT3; TAF10; PFDN5; BACH2; ETV5; JUP; SETD3; MDM2; NFATC3; ZKSCAN1; PITX1; ZNF654; ZNF512B; BNC2; DEK; YBX3; TAF1D; ZNF281; RBPJ; KLF11; FLNA; HMGN3; ZNF467; TBL1X; KDM5D; HDAC9; CEBPB; TBX3; SAP30; ST18; SIX1; WWC1; PHF20; WWTR1; PDLIM1; KLF2; RSF1; MEIS2; NKX3-1; THAP11; SHOX2; TP63; MAFB; TRIM22; OSR2; PEG3; SNAI2; BHLHE41; POU2AF1; MEIS1; TBX2; GATA2