Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09634 Barasertib-hqpa GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 106 GATA3; TULP4; EDF1; SOX4; PAX6; KLF6; CREM; MLLT10; KMT2A; CBX8; BCL11B; HSBP1; ZMYND11; NFYA; HOXA1; CAMTA1; EZH1; IKZF5; PHOX2B; HAND1; SP1; REL; PRDM4; DNAJC1; ASCL1; ZNF33B; ZNF721; ELF5; SOX10; HTATIP2; NR1H3; TCF7; ZNF611; INSM1; MAF; ZNF665; DNMT3B; HIPK3; TBL1X; ZNF506; RBBP7; NR1I2; ZNF253; CD3D; TOX3; PGR; AFF4; ZNF165; EBF2; KLF3; NFIB; IFI16; ZNF107; NPAT; ZNF292; CREBZF; EPAS1; GTF2I; ATF7IP; BARX2; RBBP4; LYL1; RNF4; ZNF711; ZNF83; NKX2-2; SMARCE1; KLF4; CNOT6; ZNF22; ZKSCAN1; HOXB7; ZNF552; CTNNB1; HEY2; NR5A2; JUP; DDX5; CARHSP1; EN1; AHR; ST18; TGIF1; KLF9; SIAH2; ID4; TBX3; ERG; HOXC6; TAF1D; VDR; PPARG; NR1D2; SSX1; TFEC; MYCN; RUNX1; RBPMS; HOXC10; TXNIP; ZNF652; ZNF160; SOX9; PIR; HEY1; SATB1
Down-regulation 62 BRD4; RFX5; TEAD4; ETV5; CCNE1; NFIC; YBX3; PREB; ZFP36L1; MAZ; STAT1; EMX2; HDGF; COPS2; RERE; PKNOX2; BHLHE41; ZNF512B; TCF21; MEIS2; NRIP1; ATF2; FLNA; TCF3; CARM1; CUX2; AR; ZNF148; NR2F2; WT1; ZBED2; TCF4; ZNF12; HMGB1; CBFB; ZNF217; NLK; CRYM; KLF10; ARID1A; ARNT2; BRD2; GTF3A; WWTR1; SIX1; PRRX1; MED13; NKX3-1; MEOX1; SIX2; MKL2; MXI1; TWIST1; ZNF331; PBX3; RBBP8; MEIS1; TRIM22; POU2AF1; ZBTB18; PEG3; GATA2