Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09633 Barasertib-hqpa GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 70 RELB; ARL2BP; ZNF576; ZNF75D; PMS1; NCOA3; HOXC4; POU4F2; THAP10; IRF2; ARID3A; OLIG2; NKX2-2; PREB; TRIB3; PROX1; ZNF112; TERF2; ZNF232; NFKB1; ZNF189; CBX7; ETV5; TBL1XR1; LPIN2; NFAT5; EGR4; ZNF606; SFMBT1; HOXC10; CEBPB; HOXD11; CREB3L2; TCF4; TDP2; UBE2B; RUNX3; EHF; ZNF415; ZNF532; FOXO1; SUB1; NR1H4; SALL2; EGR2; ERF; PRRX2; HOXC6; NR0B1; HDAC9; TWIST1; BCL3; SPIB; NPAS2; INSM1; AFF1; BHLHE41; PITX1; ZEB1; IRF8; PBX1; MYRF; PEG3; ZBTB20; MYCN; HOXD1; ZHX2; NFE2L3; POU2AF1; TSC22D1
Down-regulation 32 PUF60; PAWR; ARRB1; HSBP1; TOX4; GTF2I; LMCD1; ATF4; BIRC2; DEAF1; XRCC6; ID4; SOX10; RORA; MITF; FLNA; PCGF2; AEBP1; ELF5; PLAGL1; KDM5D; SMARCA1; SMAD7; IRX5; HTATIP2; KLF4; WT1; SATB1; MYBL1; TOX; GATA2; TBX2