Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09631 Vemurafenib GSE70138 HA1E Human 24h 0.04uM EID0003
Types Number Response transcription factors
Up-regulation 41 SPDEF; HOXD3; PAX6; EHF; AR; PPP1R13L; HOXD1; ZNF248; HSBP1; TSC22D1; CHD9; EN1; NKX2-2; DNAJC1; PLAGL1; ZSCAN31; MAF; RNF141; PEG3; ATF3; NR4A1; KLF6; NPAS2; BHLHE41; ST18; IRF6; ID4; SOX9; HOXB13; ZNF160; MEOX1; TFAP2C; INSM1; TP63; PDLIM1; PBX1; TRPS1; MEIS1; TRIM29; BTG1; TOX3
Down-regulation 28 PBXIP1; DDIT3; IRF2; STAT6; TGFB1I1; SMAD7; ZNF217; VDR; RXRA; HEY1; ZHX2; ZBTB18; ERBB4; PIR; KLF2; MAFB; HTATIP2; KLF10; ELK3; FOXC1; POU2AF1; KDM5D; MXI1; SATB1; ID1; GATA2; PPARG; TBX2