Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09629 Vemurafenib GSE70138 HA1E Human 24h 0.37uM EID0003
Types Number Response transcription factors
Up-regulation 94 GABPB1; MAGED1; POU2F1; BAZ2A; ZBTB1; KMT2A; PHF8; FOXN3; ZBTB44; ZBTB20; HMG20A; TRIM33; RORA; SOHLH2; KAT2B; UIMC1; MED14; AFF2; LIN28A; ZNF611; DNMT3B; CBX7; ATF7IP; NFE2L3; BCOR; TP63; PHIP; CREBZF; HES1; CD3D; PBX1; ELK1; SALL2; TCF21; ZIC3; BPTF; RBPMS; NKX2-1; ISL1; NR0B1; PGR; RCOR1; MEIS2; POU5F1B; TAF7; HMGB3; NANOG; CEBPZ; BCL11B; TRIM16; BAZ1A; CUX1; TCF12; RUNX3; ZMYND8; CITED2; NR2F1; E2F8; ZNF160; ZNF532; ZBTB16; SSX1; STAT4; PLAGL1; ASCL1; CTBP2; CRYM; TFEC; RSF1; ZNF721; IRF8; TLE4; ID1; JUNB; NR1H3; ETS2; ZNF652; PPARG; KLF10; HTATIP2; IKBKAP; SPIB; ZFPM2; IRF4; AEBP1; PEG3; TOX3; TSC22D1; TOX; TFAP2C; EGR3; MAF; SOX11; GATA2
Down-regulation 51 CRY1; BIRC2; PCGF1; NCOA6; CEBPG; NRIP1; KLF6; SNIP1; PEX2; RBBP4; HDAC1; RFXANK; SOX9; MSX1; FOSL2; RBPJ; RNF14; POU4F1; BHLHE40; ZNF24; NFIC; SMAD6; KLF9; ATF4; NFIB; BRD4; ZNF91; RBBP8; ZNF226; BHLHE41; APEX1; GTF2IRD1; PTRF; ZNF217; ERG; PHF20; ATF3; ELK3; PDLIM1; EPAS1; ID4; ZNF165; ABL1; GTF3A; TRPS1; TWIST1; FOSB; MECOM; MAFB; HEY1; PBX3