Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09628 Vemurafenib GSE70138 HA1E Human 24h 1.11uM EID0003
Types Number Response transcription factors
Up-regulation 83 SPDEF; HIPK1; TSC22D3; PNRC1; HSBP1; HBP1; HDAC5; ZNF227; FOXJ1; HLF; ZNF232; ATF3; HMGA2; BRD8; ZNF665; TFCP2; ZBTB16; ZNF45; ZSCAN18; TAF1A; TGIF1; PBX1; ZEB2; CNOT2; MECOM; LMCD1; BCL11A; CEBPB; ZNF266; ARNTL2; DNMT3B; ZNF544; ZNF133; OVOL2; IFI16; FLI1; HLTF; NR3C1; SSX1; ID4; GATA6; CTNNB1; ZNF302; TFEC; CREBL2; IRF1; ZIC3; RREB1; ZNF175; FOXO1; TAF7; HMGB2; MAF; JARID2; TSC22D1; ETS2; NFIB; ZNF22; PIR; TLE4; ARNT2; NANOG; KAT2B; ZHX2; ZNF423; HEY1; LIN28A; TRIM22; TBX3; TOB1; ZFPM2; ZBTB18; PPARG; HTATIP2; TXNIP; KLF4; LEF1; ID3; AHR; MXI1; MYB; SATB1; KDM5D
Down-regulation 64 SND1; CCNE1; BAZ2A; TGFB1I1; ING2; ZBED2; RORA; ETV5; COPS2; BRD4; CBX4; WT1; TGFB1; CARHSP1; ZNF148; FOXD1; KMT5A; MEF2A; CREB3L2; ESRRG; NFAT5; HOXA11; ESR1; HOXD11; CUX1; CRY1; PA2G4; SREBF1; HDAC9; NPAS2; BBX; FLNA; ATN1; CLOCK; C1D; MED13; MTDH; IL16; AES; NKX3-1; HOXB6; HMGA1; ELK3; PTRF; SIX1; IRF7; KLF10; NR2F2; EHF; CERS6; HOXB7; BRD2; CTBP2; PTTG1; HOXC10; ZBTB38; RBBP8; EYA2; HOXB2; HOXC6; ELF3; ASCL1; DACH1; TBX2