Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09627 Vemurafenib GSE70138 HA1E Human 24h 3.33uM EID0003
Types Number Response transcription factors
Up-regulation 78 NFKBIB; ETS2; GFI1B; SAP30; CITED2; ZNF688; ID4; PAWR; PIR; FOXJ1; MAX; AHR; TTF2; HOXB5; KLF5; HOXB2; ZEB2; FOXN3; HOXB6; SALL1; RELA; PGR; TLE4; BCL6; SALL2; SSBP2; SP2; AR; RCOR3; HIPK3; NR2C1; TOX; TCEA1; CHD8; EMX2; ZNF266; TAF9B; ZFP36L1; ARID5B; ZSCAN18; KAT7; PAX6; PRKDC; RBL2; FLI1; ZIC3; SOX13; PLAG1; HMGA1; CEBPG; HLX; TFEC; NR1I2; MEIS1; MAFB; PBX1; SOX17; TOB1; IRX5; TXNIP; ISL1; MNDA; TRIM22; NKX2-2; LIN28A; TAL1; ZNF423; NPAS2; ZHX2; NANOG; ELF5; MEIS2; MEOX2; ERBB4; GATA2; DACH1; PEG3; SATB1
Down-regulation 57 CRK; TLE1; NR2F2; SP3; DNAJC2; NRIP1; CDC5L; SLC2A4RG; BCL3; TTF1; PIAS1; CITED1; BCL10; ZKSCAN1; RBPJ; SUB1; CUX1; PRRX2; HIRA; MED6; WWC1; ARNTL; CBFB; FOXD1; NFATC3; CREB3L2; STAT6; TBL1XR1; SMAD7; SIX1; CCNC; PTRF; UBE2I; CERS6; MYRF; GRHL2; MBD2; PITX1; MLXIP; HOXC6; BCL11A; JARID2; LITAF; COPS5; ZBTB38; NFIB; ABL1; JUNB; GATA6; SOX9; IRF4; FLNA; LEF1; HES1; NR3C1; TBX2; PPARG