Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09626 Vemurafenib GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 79 STAT5B; MNAT1; MECP2; ATF4; TRIB3; TXNIP; TDRD3; CIITA; FOXN3; HLF; NCOA2; FOXF2; RXRA; PSPC1; ZNF131; TGFB1I1; HIC2; CBX4; TDP2; STAT5A; ZNF177; PBX1; TAF9B; DDIT3; CBX7; TERF2; DDX17; ZNF32; HOXD11; TCEA1; TSC22D3; ZEB1; ARID5B; KLF5; ID4; NR4A1; PURA; ATF3; PAX6; ASH2L; LYL1; KLF4; VGLL1; ZFPM2; OSR2; CITED2; APEX1; NKX2-2; TP53; NR3C2; JUP; HMGB2; TCF12; TFAP2C; KAT2B; NR2F1; MEIS2; NFE2; IFI16; PPARG; JUNB; MECOM; ZNF423; ZMYND8; CEBPB; AEBP1; RBBP8; FOXF1; ZSCAN18; TWIST1; ARNT2; ELF3; PEG3; ID1; MYRF; GATA2; TOX; PSIP1; SATB1
Down-regulation 49 RFX5; EGR1; PIAS3; NRIP1; BHLHE40; HMGB3; CD3D; HMGA2; LEF1; ZNF281; GATAD2A; ZNF430; HMGN3; REST; BCL10; STAT6; FOXD1; HDGF; BCLAF1; C1D; NRBF2; STAT1; SFPQ; ZNF146; CREB3L2; TMF1; SIAH2; ZNF107; HTATIP2; IRX5; YBX3; MAGED1; IRF4; CHD7; ZIC1; RORA; YWHAB; KLF10; AFF1; TRIM22; ZBTB18; PAX5; SPIB; HOXB2; ASCL1; MAF; HES1; TBX2; NR3C1