Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09608 Hg-5-113-01 GSE70138 HA1E Human 24h 10uM EID0003
Types Number Response transcription factors
Up-regulation 640 CEBPD; ZNF394; ZNF10; GABPB1; SALL2; ZNF264; NFE2L2; ZNF180; ZNF304; CTCF; ZNF432; ZNF408; ZNF227; ZNF34; MECP2; ZNF274; EP300; ZNF211; ZNF350; ZSCAN32; ZBTB3; PPRC1; SAP130; HIC2; SIRT7; HDAC4; ZNF573; ZNF142; ZNF8; ZNF222; SPDEF; ZNF154; ZNF529; ZBTB39; ZNF45; MAFB; ZBTB11; ZNF174; L3MBTL1; HDAC5; PRDM2; ZNF500; BCOR; CIITA; ZNF112; TBX19; ZBED2; ZNF571; MED17; ZNF184; ZNF324; ZNF134; ZNF711; PLAGL2; ZBTB43; ZNF778; ZNF235; KLF11; ZNF273; ZNF415; PIAS4; GBX1; NFKBIB; ZNF787; PRDM10; ZNF263; SUV39H1; ZNF667; ZNF345; ELF4; ZNF225; NCOA2; FOXO4; GCM1; ZNF14; SCAI; RORB; MNDA; MEF2C; SCAND1; ZNF623; ZKSCAN4; PBXIP1; ZNF551; NRF1; ZNF117; CBX4; DDIT3; ZNF136; ZNF473; BCL11A; HESX1; ZBTB6; ZNF239; ZNF197; TAF5; MED12; ZNF510; ZNF236; ZNF75D; ZNF629; ZNF544; IKZF5; ZNF589; E4F1; TCERG1; NUP62; ZNF426; ZNF84; SIX6; ZNF550; RFX3; PRDM14; ZNF107; LDB1; ZNF223; TERF2; RRN3; ZBTB17; HHEX; ZNF562; CBFA2T3; RNF6; ZNF492; ZNF214; ZNF282; TRAF6; ZNF695; ZNF83; HINFP; POU1F1; FOXJ2; KDM4A; SOX21; CUX2; ZNF764; ZNF668; BRPF1; TAF1C; HCFC1; ZNF443; ZFP64; SETD2; ZNF212; ZNF813; MAML3; RFX1; TBX4; SOX5; PBX1; NR6A1; MAFG; ZSCAN9; RLF; BCL6; DPF2; SOX3; ZBTB44; GMEB2; ZNF484; ZNF671; FOXH1; ZFP30; ZNF407; KAT6A; ZNF574; BRWD1; IRF1; ING1; ZNF549; CHD2; ZKSCAN8; ZNF696; CALCOCO1; ZNF80; DMRT1; ASXL1; RUNX3; NANOG; SAFB; ZNF780B; ZNF674; ZNF614; ZNF7; MBD4; ZNF257; ZXDB; ZFP2; ZNF814; TP73; GCM2; FEZF2; ZNF74; THAP9; TAF4; TRIM33; IRF8; ZBTB48; PAX1; BRF2; ZNF81; SNIP1; SUPT7L; SNAPC4; ZNF682; ZNF131; MYF5; ZNF391; MED14; PAX6; ZNF460; HIPK1; ZNF202; ZNF613; RBM39; ZNF254; TCF7L2; NEUROD1; RING1; NR5A1; TFEC; ZNF749; TRIM24; SIN3B; PGR; ELF2; NKX2-2; HOXB1; ZNF362; PKNOX2; NR2E1; SCRT1; CRTC1; ZNF287; ZNF234; HNF4G; BRDT; ZNF157; DBP; PAX4; ZNF512B; ZFY; SP4; ZNF442; PDX1; ZNF419; GSC2; ZNF79; ZNF43; HOXC5; ZNF480; ZNF688; PAX3; HMBOX1; THRA; ZNF219; ZFX; TLX3; ASCL2; ZBTB7A; AFF3; TBR1; ZFP37; ZNF468; MXD1; PPP1R13L; PCGF1; PPARA; ZNF701; HES2; USP21; ING4; MYNN; ARID4B; PAX7; ZNF471; ZNF770; CNOT2; ARID3B; TONSL; ZNF440; HIF3A; ZSCAN12; ZNF334; ZNF493; NEUROG3; THRB; ZNF606; TAF7L; HSF4; CIR1; ZNF324B; MSX2; KAT8; TFAP2A; DOT1L; POU6F2; ZNF91; YY1; JARID2; ZNF221; ZNF177; JAK2; SOX13; MEF2D; ALX3; HNF4A; TULP2; ZNF587; MLLT10; ZNF268; HIC1; CARF; VPS72; ZNF41; ZNF141; ZNF224; TAF1; FOXD3; CDX4; NHLH2; NKX2-5; ZNF783; WT1; NKX3-2; ZKSCAN7; NEUROD2; ZNF195; TRPS1; SHOX; NEUROD4; TAF1A; INSR; ZNF208; AR; ZNF506; NONO; ADNP2; PITX3; ZBTB40; MYB; GATA1; KLF13; ASH1L; NR1I3; TULP1; ZNF16; IRF3; ZNF165; BNC1; VGLL1; SOX12; ZIC3; WHSC1L1; SMARCD1; EZH1; NEUROG2; ELK4; SOX18; IRX4; ALX4; MXI1; ATF4; NKRF; HMGXB4; ZNF250; KMT2B; YAP1; PRDM5; CHD1; TRIB3; POU4F3; TGS1; ATOH1; MZF1; TLX1; SOX15; POU2F3; ZNF85; THAP1; ZBTB20; ST18; ZNF44; NR2C2; ZNF175; LHX2; HOXD3; FOXE3; CDC5L; ZNF132; PLAGL1; TEF; ZNF135; CBFA2T2; POU2F1; ZNF654; BACH2; CREBZF; ESR1; ATF2; TAF4B; FOXO1; ZNF556; ZBED4; MAFK; ZNF232; PRDM9; SRY; MYEF2; CBX2; RREB1; CAMTA1; TCF3; ETV2; INSM1; LYL1; MYCN; NHLH1; ZNF133; HOXD12; VHL; PAXBP1; APBB1; RCOR1; ZBTB24; PIAS1; THAP10; CDIP1; SIRT2; ETV7; MAML1; CERS6; HBP1; PFDN5; ZEB2; ZNF580; NR4A2; DCC; SAP18; VENTX; TCF4; KDM4C; HIVEP1; SOHLH2; PEG3; PHIP; CEBPG; NCOA6; HOXD13; ZNF93; RSF1; FLI1; STAT2; ZNF331; NKX6-1; HOXA2; OLIG2; NR1I2; EMX1; KAT6B; TEAD3; MAK; IRF4; OVOL2; CITED2; RARA; PLAG1; NR0B1; HOXA1; RCOR3; ONECUT2; SOX1; SMARCD3; ZNF3; SUV39H2; SOX14; ZNF329; ZNF24; PITX1; MYT1L; SP2; UTF1; TRAK1; MLLT1; HLF; SNAI1; ZFP36L2; TCEA2; MSC; TTF1; SMAD7; BACH1; TAF6L; GON4L; TAF5L; IKZF3; NR1H2; OVOL1; NR1H3; PROX1; OSR2; ARNT2; ZSCAN31; ZSCAN16; MITF; PCGF2; PRRX1; CHD7; NAB2; ZNF143; GLI3; ZNF423; RARG; SPEN; LHX3; MED23; EN2; PAX5; ZHX2; CBX5; PNRC1; ZNF124; E2F3; ZNF337; ZNF354A; HEY2; TEAD4; ZNF652; KAT2B; VDR; NEUROD6; BPTF; CREB5; THAP4; BTAF1; FOXF2; ZNF266; TWIST1; CBX7; HIRA; MGA; TMF1; PHF20; PAX9; ZNF267; REPIN1; FOXA1; ERBB4; ERF; HOXD1; ZNF665; NCOA3; SPI1; ZNF536; TBX1; ETV5; EGR4; ERG; LHX6; DAXX; LIN28A; BHLHE41; SIAH2; ZFPM2; SOX17; FOXJ3; POU3F2; ARNTL; ZMYND8; SKI; TAF1D; DLX2; MAF; RAD21; ZIM2; NR5A2; TOB1; NR2C1; ZBTB18; SIX3; GFI1; RNF138; ZNF532; SOX11; IL16; ZNF430; SUPT4H1; GLI2; NFATC1; ZNF140; REL; AGO2; TERF1; ZNF516; TULP3; POU4F1; ELF1; MYCL; SP140; HSF2; TOPORS; NR1H4; RYBP; DLX5; RXRG; THAP11; AHR; E2F5; ID3; TAL1; HLX; MEIS2; RXRA; TRIP6; SSBP2; CREB3L2; TCF7L1; BRD4; ZNF721; HDAC9; ZBTB16; NPAS2; SNAI2; MEIS1; GTF3A; NFAT5; ZSCAN18; SHOX2; GATA3; SPIB; KDM5D; CEBPB; MYRF; DACH1; POU2AF1; PBX3; HOXB2; ID1; E2F2; ABL1
Down-regulation 121 CRK; FHL2; GTF2A2; PAX8; PSMD9; TFDP1; LOXL2; BRCA1; MYCBP; ATF6; VGLL4; SMARCC1; HDAC2; RUVBL1; PARP1; KLF6; HDAC6; WDR77; SOX4; HIF1A; ITGB3BP; NCOR2; SMARCE1; ENO1; MNAT1; TBP; FOSL1; MYC; SMAD3; HNRNPD; HOXC6; FOXD1; USP22; KLF2; EDF1; TRIP4; SMARCA5; CCNA2; RBPJ; STAT6; TRIM16; RBBP8; ACTL6A; EED; ETS2; CCNC; HOXC10; TCF12; KLF12; PRMT2; ERBB2; SMAD2; YWHAB; NR2F2; ELF5; NEDD8; HSBP1; ZMIZ2; ATF5; RB1; MED7; NR2F6; HDAC1; SETD3; TBPL1; FLNA; RNF14; WWC1; STAT1; PSMC3IP; ZBTB38; PTRF; PSMC3; USP16; MBD2; DMTF1; NPM1; NELFB; SLC2A4RG; CBX3; HLTF; CBFB; CREB3L1; NFIB; KLF9; PSIP1; CSDE1; AES; BCLAF1; BHLHE40; IFI16; SIX2; HOXB7; TP53; HMGB2; BRD3; RAN; RBPMS; ELF3; UBE2I; HMGB1; MYBL1; STAT3; HOXA10; WWTR1; TXNIP; HMGN3; TBL1X; TSC22D1; RUNX1; CTBP2; GATA6; AFF1; LMCD1; PTTG1; FOXC1; HOXB6; LEF1; TOX3; SATB1; PPARG