Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09606 Geldanamycin GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 38 ADRB2; NFKBIA; NR3C1; RELB; RNF111; PPARGC1A; HIVEP2; SP100; HMGN3; FOXC1; SP140L; PHF20; MAZ; ELF1; NFYC; SMAD7; HNRNPD; SIX1; FLNA; SFPQ; BBX; TRIM28; SP3; BCL3; TOB1; BRD8; BMI1; NR1D2; ZBTB38; TRIM22; HLTF; NR2F2; ZEB2; MAGED1; ASCL1; AFF1; ENO1; NFATC3
Down-regulation 130 HOXA5; GATA6; HOXB5; TAF12; DLX2; HOXA7; NFX1; HNF4G; ZBTB7C; PAWR; CERS4; KLF1; PBXIP1; PBX1; LEF1; FEZF2; BACH2; GCM1; ZIC3; ZNF500; ZNF688; HMGA2; BCL11A; TFEC; DLX5; LIN28A; THRA; OVOL1; MXD1; NR5A2; SOX2; ZNF254; ZNF93; HOXB2; KLF3; CSDC2; FOXE1; SSBP3; ZNF675; ZNF117; MEIS1; HOXB6; MBD4; HOXA2; TCF4; ATOH1; ZNF345; ZBED1; ZBTB3; THRB; AEBP1; CREM; SATB1; PRDM14; TCF7L1; SNAI2; NFE2L3; ZIM2; ZNF273; ZNF440; NR1H3; SP4; ZBTB25; PAX5; TRIB3; ZNF136; MNDA; SOX3; VGLL1; ARNT2; NANOG; SOX11; FUBP1; KLF11; SPIB; KLF5; CD3D; SPDEF; ZNF711; ZNF257; ZNF141; ZNF83; NKX2-2; EN1; ZFPM2; GRHL2; POU2AF1; HDAC5; E2F5; TWIST1; OLIG2; FOXA1; ZNF573; ZNF43; ZNF682; SOX17; KLF4; TAL1; SALL2; PBX3; ZNF415; IRF6; EHF; WT1; ZNF331; SSX1; INSM1; ZNF232; NEUROD1; DACH1; ZNF165; CBFA2T3; HIC2; PAX6; ZFP36L2; SIX3; ZNF91; ZHX2; MYB; ID3; NR4A2; ZNF589; PEG3; TLE4; TXNIP; TFAP2C; ZNF586; ERBB4; MEF2C; PPARG