Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09604 Geldanamycin GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 78 FOXO4; SUPT5H; CALCOCO1; PHF8; ZNF384; MZF1; CEBPD; ZNF45; CENPF; CITED2; ZNF580; PSPC1; SETD2; TCF25; ERCC3; TRIM28; BRF2; CREG1; PHF1; BRD8; CHD3; PFDN5; TEAD3; IRF3; COPS2; RSF1; ATF5; MAX; HCFC1; WHSC1; TMF1; NR2C1; ZMYM2; ELF1; NFAT5; MAZ; RORA; NCOA3; RNF6; HMGB2; ZNF432; E2F8; CEBPB; SMARCD3; PIAS1; INSR; RERE; AFF1; ARID1A; POLR2A; CBX7; MAGED1; STAT5A; ZMYND8; CTR9; HMGB1; NONO; PIR; KMT2A; BAZ2B; MED23; CSDE1; ATF4; ETV5; RFX5; RBPJ; EYA2; TSC22D4; ELF5; MYRF; ZBTB16; PBX1; TRIP6; THAP11; SMARCA1; ZNF331; HLTF; IKBKAP
Down-regulation 86 FOSL1; BHLHE40; NFKBIA; EGR1; KLF10; SNAI2; KLF6; DRAP1; KLF7; DLX2; SOX4; STAT3; TCFL5; WDR77; ELK3; REL; TLE1; RUNX1; DACH1; ID4; NFKB1; PTRF; ID1; BACH1; MYC; SATB2; TRIM29; HOXA10; ID2; LMCD1; HSBP1; MXD1; CBFB; IRF7; SCAND1; SERTAD2; TGFB1; BTG1; EGR4; PAWR; PRRX1; ZMIZ1; GATA6; AHR; SPIB; JUN; NR4A3; PSMC3; KLF4; TFEC; POU2AF1; LIN28A; SMAD7; PAX5; SMAD1; EGR3; ID3; HES1; E2F5; NFATC3; MAFB; TBX3; SOX9; EGR2; TCF4; PBX3; PDLIM1; IRF6; TWIST1; ZNF652; ENO1; HHEX; TRPS1; IRF8; JUNB; ZFP36L2; TLE4; INSM1; ADRB2; MYBL1; TOX3; NANOG; SATB1; ZNF586; WT1; PPARG