Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09603 Geldanamycin GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 78 NFKBIB; FOXO4; CEBPA; SUPT5H; ZNF432; PFDN5; PHF8; BRD8; WHSC1; ZNF45; ZFP64; MAML1; SFMBT1; ARID4B; NFE2; CHD3; CALCOCO1; RSF1; RFC1; ATF1; RUVBL2; PTTG1; MAZ; MXI1; SMAD3; CITED2; TAF5; MGA; CREG1; SF1; RERE; RCOR1; CEBPD; ATF5; CIC; NCOA3; RBM39; SETD2; ATF7IP; HMGB2; DBP; LPIN2; BBX; NCOA4; MLXIPL; TMF1; CENPF; CCNC; FOXK2; ASH2L; AFF1; BRD3; EYA2; TRIM29; DDIT3; NONO; ZMYM2; CNOT3; NCOA2; ETV5; PNRC1; CTR9; CALR; TRIM28; LITAF; PCGF2; TGIF1; RORA; ZNF544; ATF4; MAGED1; INSR; HLTF; BMI1; SAP30; ZNF331; NFATC3; PEG3
Down-regulation 121 FOSL1; RELB; EGR1; RUVBL1; KLF6; DRAP1; KLF7; JUN; LMCD1; SNAI2; DMTF1; SATB2; ELK3; GATAD2A; NFKBIA; FOXO3; KLF10; APEX1; CREB1; HIRA; SOX4; TGFB1I1; BHLHE40; DLX2; ZNF3; BIRC2; WDR77; NFX1; NR4A3; PAWR; CUX1; POLR3C; PRRX1; GATA6; ARL2BP; NFKB1; TSC22D2; HOXA10; HOXB6; ARNTL; FOXA2; HES1; PTRF; NKX3-2; CERS6; TCF7; CTNNB1; ZNF107; MLXIP; HOXD3; NR4A1; HIVEP1; FOXL2; ZMIZ1; EN1; ZNF512B; KLF2; WT1; OVOL1; IRF7; SCAND1; TWIST1; FOXG1; BCL10; BACH1; KLF4; PDLIM1; RBPMS; EGR2; TAF1A; BTG1; JUNB; TAF1D; ATF3; FOXD1; OLIG2; MEOX2; MYC; STAT4; HSBP1; TFEC; SOX9; AEBP1; ZNF254; ZNF273; PAX6; ESRRG; EGR3; SERTAD2; TRIB3; ADRB2; ZNF91; REL; SPDEF; TLE1; ID4; MEIS1; HOXB7; FOS; RUNX1; TBX3; CBFA2T3; LIN28A; NFKB2; ETS2; ID3; MYBL1; IRF6; IRX5; NKX2-2; SIX3; TCF4; TFAP2C; NANOG; ID1; TLE4; MEF2C; SSBP2; ZBTB18; PPARG; ZNF586