Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09602 Geldanamycin GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 111 TBX2; KDM5B; STAT5B; RHOA; EHMT2; PCGF1; ZNF384; FOXO4; KDM5A; ZNF282; CEBPD; CNOT1; CCNA2; RUVBL2; ARID4B; E2F6; ZBTB40; CITED2; SUPT5H; ZNF629; ZNF24; SIX2; TEAD3; DBP; ATF1; MAZ; RERE; KAT5; TRIM28; ZNF212; KMT2B; MZF1; CHD3; SND1; ZNF473; RXRB; ATF7IP; RBFOX2; CREG1; HDAC7; PFDN5; LITAF; IRF3; TCF25; ZNF45; CALCOCO1; EZH2; PATZ1; ARID1A; BAZ2B; BRD8; NFYA; PIAS1; SSRP1; EYA2; TRIP6; MTA1; CREB3L2; TCF15; CENPF; NFAT5; ZBTB38; RNF6; BCLAF1; BAZ1B; CDC5L; FOXC1; HDGF; BCL11B; ALX1; RBL2; RNF10; RXRA; HLTF; HMGB2; ZMYM2; KLF5; SPEN; CNOT3; NR2F1; BMI1; BBX; PTTG1; AR; MEIS1; DPF2; CSDE1; HDAC1; ZNF146; TSC22D1; AFF1; RBPJ; TSC22D4; PDLIM1; EHF; NCOA1; TCF7L1; PCGF2; MAGED1; KLF9; CREB1; BCL3; TOB1; FOXF1; MSX1; PBX1; PSIP1; HDAC2; KDM5D; FLNA; SOX11
Down-regulation 164 FOSL1; EGR1; ETS1; RELB; JUN; ZNF32; EGR3; DLX2; ZNF593; KLF10; WDR77; BHLHE40; PQBP1; NFKBIA; IFI16; SNAI2; LMCD1; NFE2L3; GABPB1; TFDP1; ZNF268; SOX4; SP110; KLF6; PEX2; EGR2; BIRC2; NR2F6; KLF7; LIN28A; MAFG; ZMIZ1; WWP1; HIF1A; PRRX1; ELK3; FOXO3; MED7; CREB5; ENY2; DAXX; SATB2; BACH1; GATA4; BRCA1; TSC22D3; TWIST1; LEF1; SCAND1; ZNF562; ZNF281; HOXA10; SERTAD2; ZNF552; ZNF654; PRKDC; FOXN3; TBPL1; SOX17; TRIM22; TCF7; NR2C1; PBX3; GATA6; SMARCC1; TAF1D; DMTF1; COPS5; ZNF93; KLF2; ANKRD1; MTF2; NANOG; TRIM29; E2F3; BHLHE41; MAFF; USP22; CEBPG; BCL10; MYBL1; ZNF217; ZNF623; ATF3; FOXL2; ZNF44; TAF1A; POU5F1B; SOX2; ZNF267; IRF7; ZNF107; IRF9; TRIB3; CREB3L1; VENTX; DNMT3B; ZNF136; ZFPM2; ZNF91; ZIC1; KLF4; PLAGL1; TCEA1; ZNF232; HDAC9; CBFB; MAFB; HHEX; NCOR2; ISL1; BNC2; ETV5; ZNF423; TBX1; AEBP1; TFAP2C; RBBP8; ZNF430; HOXB6; NKX2-2; ZNF426; KAT2B; RUNX1; ZNF273; REL; ZNF43; TLE1; SPDEF; HSBP1; SPIB; EN1; NKX3-1; WT1; ZNF573; CEBPA; KLF3; BACH2; NPAS2; MYC; ZBTB18; ZIC3; ZHX2; KLF11; ID3; ERG; HES1; MAF; FLI1; ZNF721; TLE4; ID1; ZNF589; HEY1; PEG3; TRPS1; FOSB; HIC2; SATB1; ST18; MEF2C; PPARG; ZNF586; ESR1