Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09595 Withaferin-a GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 108 IKZF1; CNOT2; KDM5D; ELK4; PFDN5; SP110; CERS4; HBP1; DNMT1; INSR; SIX2; ZBTB16; NR2F1; SUMO1; HMGA1; CEBPD; MYBL2; FOXA1; ZNF580; FOXG1; SOX2; HLF; PITX1; TDP2; RORA; HIRA; LHX3; SP140L; FOXF2; CREB3L2; TRIM24; NFIC; HDAC4; ZNF140; IRF9; CNOT3; SOX11; NR2E1; ZNF350; AR; SPDEF; ARNT2; ZNF654; CHD9; TP63; CBX4; SOX3; CUX2; SALL2; TP73; MKL2; NR0B1; NEUROD6; STAT4; NFE2L3; ZNF232; PKNOX2; PRDM2; JUN; NKX2-2; ZNF32; ZNF652; TRIB3; CEBPB; ZFPM2; FEZF2; ZMYND8; SOX18; SOX5; ZFP36L1; PRDM14; JUND; SALL1; BRD4; KAT2B; ZHX2; HIPK2; ZNF91; NR1H2; MED13; ZNF467; PBX1; TAL1; FOS; TCEA1; MNDA; SPIB; ZBED2; TRPS1; ZNF589; ZNF415; ZNF423; ZNF117; ID4; ZNF331; AEBP1; PEG3; WWTR1; LITAF; CBFA2T3; ZNF264; IRF6; THAP11; TCF4; SOX9; MEIS2; TFAP2C; ERBB4
Down-regulation 47 KLF6; STAT3; DNMT3B; ZMIZ2; KLF10; NFE2L1; NRIP1; EDF1; SNW1; HSF2; BHLHE40; FOXC1; SMARCA5; PTRF; BCLAF1; BMI1; MTDH; SOX4; ELK3; KAT7; TSC22D2; HMGA2; NEDD8; HMGB2; HOXC6; IRX5; CRY1; KLF2; HNRNPD; SIAH2; CBX3; ZNF468; DPF2; SMAD7; SUB1; SERTAD2; FOXD1; HDAC1; AHR; ZNF146; MED1; EGR2; MSX1; HTATIP2; NR2F2; ZBTB18; NR3C1