Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09593 Withaferin-a GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 47 HMGA2; HMGA1; CCNH; VGLL4; HOXB13; BACH2; CEBPB; PMS1; CREB3; CEBPZ; NFATC1; TERF2; HOXD1; ARNT2; CHD9; TDP2; CRYM; ZNF239; ELF4; FOXA1; BCL11A; CBFA2T3; SREBF1; SOX2; ZNF232; SOX10; KLF4; TRPS1; SIX1; NR1H3; SNAI2; TRIB3; PAWR; YBX3; JUP; MYBL1; NPAS2; HIRA; TFAP2C; SPIB; SOX9; TBX3; FOXG1; EN1; ZNF589; SPDEF; ESR1
Down-regulation 48 NFKBIA; RELB; NRIP1; PBXIP1; BHLHE40; KLF10; NKX2-1; SNW1; MED24; CRY1; SUB1; MSC; ZMYND11; ZEB2; MED1; ZNF410; FOSL2; NFIB; NCOA6; ZMIZ1; POU4F1; PDLIM1; VDR; ID4; BCL11B; HOXA10; TXNIP; SSX1; BACH1; ERBB2; MAGED1; SCAND1; BMI1; YWHAB; MNDA; SOX4; PIR; KLF6; AFF1; ZSCAN18; KDM5D; MEIS1; LMCD1; FLI1; CHD7; PEG3; NR3C1; PPARG