Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09592 Withaferin-a GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 206 NFE2; HMGA1; LDB1; E2F4; SUPT4H1; FOXG1; CAMTA2; HSF1; GATA1; ZNF473; PCGF1; ZNF75D; ZNF268; SKIL; TDP2; GTF2F1; LYL1; TRPS1; MAFG; SUPT3H; ZNF79; YAP1; ZNF557; SMARCB1; THAP4; PEX14; IRF3; ZNF211; ARNT2; WWP1; EMX2; PHF1; CEBPG; ZNF500; FOXF2; PAX5; HOXB5; CHD8; NR5A1; MYNN; TEAD3; CALCOCO1; DNMT1; PFDN5; SP140L; ZBTB48; KDM5C; ZFHX3; ZNF835; CERS4; SUPT6H; SP140; TOX; ZMYND8; ZNF354A; SRF; ASCL3; FEZF2; ZNF3; ZNF444; PBX2; ZNF764; ZNF195; CEBPD; ATF5; MLXIP; MTF2; ZSCAN9; SP100; ZNF180; TERF2; KAT6B; BANP; BARX1; CHD2; HOXB2; RING1; CBFA2T3; TRIB3; CEBPB; AIP; GCM1; ELF4; LZTR1; HOXB8; THAP7; SOX2; BCL11A; ZNF787; NR2E1; CBX4; NLK; ZNF573; BPTF; NCOA2; PITX1; E2F3; BRDT; PRDM14; PAX9; HOXD1; SPI1; POLR3C; ZBTB3; INSR; DDIT3; MED23; ARNTL; EP300; PRDM12; ZNF225; PHIP; SCRT1; ZNF749; ZNF266; CIITA; UBE2B; AGO2; ISL1; HDAC9; CNOT3; FOXA2; KLF1; ARID1A; MYRF; ATF3; TCF21; ARID3B; ZNF345; NR1H2; OSR2; ZKSCAN4; NR1H4; ZNF671; ZNF136; ATOH1; TFDP2; ZNF81; HESX1; PAWR; ZNF512B; HIC2; SCAI; NR4A1; ETV5; NR2F1; SOX5; TCF7L2; CD3D; EN1; ZNF334; RARG; TERF1; PAX4; HDAC4; LHX3; HIPK2; SIX6; ERBB4; SPDEF; MEOX2; ZNF214; ZNF711; TOB1; ZNF10; ZNF695; ZFP36L1; BRD2; BRD4; SKI; OVOL2; TFEC; SNAI2; CREM; HHEX; GFI1; FOXA1; SPIB; ZNF415; ZBED2; HOXB6; YBX3; SOHLH2; ZBTB16; TCEA1; ZNF544; STAT4; TAL1; ZNF232; HIRA; KLF3; FOXF1; HEY1; WT1; ESRRG; PEG3; ETS2; ZNF264; ZNF117; ST18; ESR1; MEIS2; THAP11; NANOG; AEBP1; TLE4
Down-regulation 96 CRK; NFKBIA; HDAC6; PSIP1; HOXA5; BASP1; CCNA2; RBBP4; ATF1; NFIL3; NFIB; ZEB2; UBP1; HOXA10; NUP62; KLF6; BAZ1A; SMAD3; BCLAF1; EGR3; STAT3; EDF1; ELK1; BHLHE40; MAGED1; XBP1; USP22; CENPF; ABL1; TEAD4; ZMYND11; EGR2; ZBTB38; IRF4; SOX4; RHOA; NPM1; BMI1; NELFB; ZBTB1; BRD3; SUB1; PCGF2; NRIP1; SMARCA2; CTNNB1; YWHAB; SMARCA4; HLTF; ELF2; TRIM32; EZH2; GLI1; NR1D2; WWTR1; SFPQ; TRIM16; ZNF32; MYC; SMARCC1; CRY1; TFDP1; ZNF22; ELF1; ZNF292; CHD7; NFKB1; PRMT2; PDLIM1; CREB1; ILF2; ENO1; PTTG1; AFF1; RNF4; LMCD1; MSX1; SP3; PBX3; MED1; ID4; CBX3; SMARCA1; TRIP6; KLF9; LITAF; JUNB; FLI1; ERBB2; ID3; ZBTB18; SAP30; BTG1; HES1; NR3C1; PPARG