Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09589	Mitoxantrone	GSE70138	HA1E	Human	24h	0.04uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	176	TCFL5; TXNIP; TBX2; SCMH1; AES; TP63; HLX; TFEB; NR1H3; SIX2; ZNF629; BATF; ST18; POU2AF1; CALCOCO1; MYCL; THRA; MEF2A; MED24; MKL2; RHOA; CBX6; ZNF529; PPARD; BCL6; CHD8; NFATC1; MYT1L; MNDA; ZNF410; ZBTB48; CBFA2T3; FHL2; ELK3; SMAD7; ZNF12; TRIM16; ZNF506; IRF5; ZNF764; TFEC; ZNF85; ZNF692; NLK; CERS6; ESRRA; REPIN1; MDM2; TRIP11; TOX3; CIITA; HDAC5; TDRD3; PEX14; TCF4; GFI1; MED6; PATZ1; MNX1; ARID4B; ZNF136; ZNF467; SRCAP; ZNF248; BHLHE40; CCNT1; FOXC1; SREBF2; MTF1; AIP; FOSL2; NR4A3; ZNF91; MAF; HOXA1; KLF4; PPARG; PDLIM1; LYL1; KLF11; IL16; MYF6; IRF2; CDIP1; MYRF; VDR; RYBP; ADRB2; TP73; HMG20A; BCL10; HEY2; TLE2; YBX1; INSR; IRF8; ZNF254; NKX3-2; NHLH2; ZKSCAN7; TOPORS; ZNF337; HCFC2; ZNF536; MECP2; ZNF711; NFX1; STAT4; CARF; ZNF43; ZNF117; ZNF507; CREBL2; GRHL2; ERBB4; JUP; SHOX2; AR; NFYC; IRF7; SOX11; ESRRG; MDM4; BTG1; CBX4; MITF; CREM; IRF4; RUNX1; CBX7; ZNF675; FOXA1; ZNF331; STAT2; ZNF492; BRCA2; ZNF107; MBD4; ZBTB18; MLXIP; SERTAD2; ZBTB25; SKI; HIPK2; MEF2C; ZNF710; MAGED1; ZBTB44; NEUROD1; KLF10; IRX5; ZNF273; HOXB2; TRIP6; INSM1; HLF; PRRX1; VPS72; PLAGL1; ZEB2; YBX3; RBPJ; ZNF124; BNC1; PRDM2; SNAI2; EYA1; FOXF2; ZNF141; TCF7L2; LITAF; TLE4; ZNF423; NR4A2; MYB; WT1
Down-regulation	158	KDM5A; LOXL2; ZNF32; CCNA2; HIF1A; RNF4; SUZ12; TERF1; YWHAB; ZNF593; TCEA1; TULP3; TBL1XR1; NPM1; CNOT1; FOXM1; SMARCC1; MAFG; ESR1; RBBP8; NFATC3; SCAND1; BRPF1; TEAD4; KDM5C; TAF7; PEX2; CBFB; WHSC1; HOXA11; TCF3; TRPS1; WWTR1; SOX17; ZNF443; VEZF1; RNF138; ZNF239; HOXA10; UBE2I; RFXANK; STAT5B; ACTL6A; KLF6; PIR; HMGA1; TAF1D; NRIP1; SFPQ; PRKDC; BRD3; ELF5; BIRC2; UBP1; ZNF84; NR2F6; SUPT4H1; TFAP2C; XRCC6; DAXX; MTF2; TOX; CENPF; CBX3; E2F3; ADNP; PQBP1; ZNF217; SMARCA1; NFIB; KAT7; HOXB7; ZNF432; TRIM28; EP300; RORA; ZNF281; C1QBP; RBPMS; CNOT2; ZNF419; TGIF1; PHF20; RAN; ATF4; NR2C1; ARNT2; DDX5; COPS5; TBPL1; DMTF1; NCOA2; RBM39; PLAGL2; CBX5; ZNF787; RBBP4; SIM2; YEATS2; TAF10; BRD7; NCOA6; ZMYM2; PHIP; MYBL1; GATAD2A; DNMT3B; CTR9; FOXL2; HNRNPD; TAF9B; ANKRD1; CARHSP1; AGO2; PTTG1; HMGB1; NONO; PSMC3; ZMIZ1; ASCL1; MECOM; HOXC6; FLNA; HDAC1; BRD8; CRY1; TWIST1; TOB1; ENO1; SMARCC2; MEIS1; SMAD2; BCL3; NFE2L3; SOX10; ZNF587; DLX5; ZIC1; NPAS2; HDAC9; THAP11; AFF1; PITX2; ZNF544; HTATIP2; NCOA1; IKZF1; PBX1; RFX5; BRD4; SOX9; MSX1; KDM5D; PBX3; LIN28A; AEBP1; NR2F2; ZNF586