Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09586 Mitoxantrone GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 500 SUPT3H; ZKSCAN1; CERS4; ZNF528; CDX1; NKX2-1; PHF1; TAF6L; HOXC5; TAF1; BATF; ZNF816; REL; SOX2; BCL11A; TERF2; INSR; RING1; ZNF688; NFIX; PBX2; CEBPE; NCOA3; FOXE1; ALX3; PROP1; ARL2BP; TWIST1; FOXF2; MEIS2; HLX; WNT4; RAX; PPARD; ZBED1; HHEX; ZNF562; RBPJL; SSX3; TGIF2; LHX3; FOXJ1; ATN1; AFF2; ESR2; ZNF358; TFAP4; LZTR1; FOXA2; NPAS1; TRRAP; GBX1; NEUROG1; MED12; VSX1; ZNF75D; NR4A2; ZNF771; NHLH1; HIF3A; TRIM25; ELK4; CDX2; HNF4A; TCF3; PGR; LEF1; SMARCB1; NKX3-2; TAF5L; TULP1; RSF1; EHMT2; CBFA2T3; CRTC1; HEY1; ZFHX2; SOX5; ZNF32; HDAC11; PDX1; ESRRB; TBX6; TAF6; TCEA2; MYB; FOXF1; ZNF770; IFNB1; ATF6B; DLX2; NR1I2; ZIC1; IKZF1; ONECUT1; SATB2; NR4A1; GATA1; NKX2-5; VENTX; TDP2; SRY; SPIB; TUB; MAK; TULP3; PKNOX2; AEBP1; TCF4; HEYL; SOX18; THAP3; E4F1; NR1H2; NR5A2; HIRA; CEBPD; ZNF556; ASCL3; ZNF444; TBX4; ETV1; YAP1; SP140L; AFF3; TFDP3; VAX2; PLAG1; CREM; NKX6-1; ZNF124; HSF4; TBX10; IKZF4; KLF15; TP73; FOXL2; ERBB4; ALX4; MAP3K10; ARHGAP35; ZNF174; RFXAP; NAB2; HOXC4; WDR77; GCFC2; ZNF177; MXI1; NR4A3; ZNF239; ATOH1; GATA4; MED25; PRDM14; ZNF500; GLI2; SOX3; NFAT5; GBX2; BARX1; PAX1; SSX7; CCNH; ZKSCAN4; SALL2; ZNF589; NR2E1; SPDEF; FOXP3; KDM5C; HOXC11; PRDM12; SIX6; ZNF835; FEZF2; NRL; PRDM9; NFE2L3; PBXIP1; PPARA; SPI1; CDX4; POLR3C; RFX1; SRCAP; HIVEP1; THRA; ZNF467; GATA6; HBP1; CARF; NEUROD6; ATF7; POU6F1; ZNF768; RARG; GRIP1; ZBTB16; WHSC1L1; ZNF154; HOXD13; PAX3; HIC2; THRB; SRF; MAML3; ZNF654; PRDM2; CD3D; NR3C2; TFEB; BACH2; PRRX2; SOX17; NR6A1; NEUROG2; ZNF221; ZNF423; ING4; ZNF557; TEF; HOXC8; ZSCAN32; TLX3; ATF5; IRF6; ZNF354A; ZNF331; CHD2; POU3F3; HINFP; DLX6; NEUROD2; HDAC5; MEF2C; SCRT1; DLX5; CRX; POU3F2; ZNF200; RFXANK; TAF1C; TBX1; NR1I3; ONECUT2; TBL1Y; ZNF219; PAX7; FOXH1; HOXD12; CUX2; KLF7; CBX2; ZNF695; SNAI1; ETV3; FOXB1; EMX1; CEBPA; TCEB2; HMBOX1; ZNF225; AIRE; SIX3; PEX14; MYF5; ZFP2; ZNF224; ASH1L; PRDM16; SOX21; ZNF573; SHOX; POU6F2; POU4F2; ZNF117; ZEB1; CREBL2; HNF4G; FOXN1; ZNF580; ZKSCAN3; TCEA1; ZKSCAN8; ZSCAN18; JUP; PMS1; ZFHX3; HOXB8; POU3F4; NR5A1; SOX14; KAT6B; TBX5; GLI3; ZNF345; ZBTB7C; ZNF33B; KLF9; HOXD1; OVOL2; ZNF287; SOHLH2; ZNF552; HIPK2; BRDT; MYOG; NFATC4; BRWD1; ZNF215; HESX1; RFX3; E2F5; POU4F3; MYF6; TRPS1; SOX13; ETV2; ZNF623; CIITA; ZBTB44; TEAD3; HEY2; SCAI; TSHZ2; NR2F6; DBP; MYEF2; IRF9; RORB; PAX4; ZFY; TRIM24; CIR1; ZNF235; VGLL1; RBL2; UTF1; MED13; PRRX1; ZNF91; ZHX2; AR; ZNF155; FOXD3; L3MBTL1; ZNF232; SSBP3; SKIL; EZH1; TULP2; GSC2; BPTF; POU2AF1; ZNF778; ZBTB48; ZNF667; DCC; KDM4C; SOX30; ERG; TFAP2A; ZNF391; NEUROD4; CERS6; ZNF140; ZNF814; BARX2; POU2F3; ZNF343; ZBTB3; PRDM1; ZNF507; ASCL2; GCM1; ZNF407; PRDM5; SP4; MKL2; JAK2; OLIG2; CBX7; SHOX2; RXRG; ZNF665; PBX3; ZNF132; IRF8; PAX5; ZNF701; GTF2I; ZNF749; FOXE3; ZNF512B; POU1F1; HES2; ZNF549; CSDC2; ZNF157; PAX9; VHL; ZNF74; OVOL1; ZNF606; PROX1; ESR1; ZNF22; CHD9; ZNF253; ZNF442; THAP9; ZNF80; ZNF214; SSX1; PITX2; PRMT2; ZNF415; MDM4; ZNF780B; NANOG; FOXI1; ZNF471; LYL1; ARID3A; FOXO1; ZIM2; HOXA2; ZNF81; ST18; JUN; POU4F1; ZNF264; ZNF362; ZFPM2; LIN28A; TBX21; RXRA; EYA1; SKI; EPAS1; BRCA2; TFDP2; KDM5D; ZNF141; ZNF710; TCF21; TFCP2; MYCL; ISL1; TRIB3; FOS; KLF11; MDM2; GRHL2; MYRF; PRDM10; TCF7L2; ID4; BNC2; ZNF430; FLI1; BRD4; TCFL5; NR0B1; GTF3A; ZNF135; NR1H4; ZNF257; GFI1; VPS72; ZSCAN31; ZIC3; TCF7L1; SMAD1; FHL5; ZNF492; THAP11; ESRRG; BRD2; ARNT2; EN1; ZBTB18; ID3; STAT4; PEG3; TCF7; PBX1; KAT2B; NKX2-2; E2F2; ZBED2; ZFP36L1; ZNF652; BNC1; CTBP2; SSBP2; DACH1; TBX2; MYBL1
Down-regulation 144 NUP62; HOXA5; NFKBIA; FHL2; XBP1; CCNA2; FOSL1; SUV39H1; TBP; ATF1; SMAD3; SNW1; NFIL3; FOXJ3; KLF10; TSC22D2; DNMT3B; CCNE1; SUB1; BASP1; PAX8; USP22; RBM14; RCOR1; HOXA10; CRK; TCERG1; SFPQ; TBL1XR1; KAT5; BMI1; APEX1; HSF2; NFIB; CENPF; CRY1; ZBTB11; RELA; ID2; BRD8; NRBF2; ECD; FOXO3; BCLAF1; RNF111; BCOR; TLE1; REST; WWC1; SMAD7; EGR1; TRIM32; TBPL1; JARID2; TRIM29; YBX1; MYC; MED4; ZNF410; EZH2; NEDD8; KAT7; BAZ1A; FOXC1; CTR9; MED6; ZNF146; TOB1; PUF60; ADNP2; CCNC; KDM2A; C1D; TSC22D1; SOX9; HNRNPD; AATF; FLNA; CEBPB; ZMIZ1; ZBTB1; ITGB3BP; RNF6; SOX4; ZNF468; MED1; RAN; SMAD2; SCAND1; PATZ1; YWHAB; CBFB; MEIS1; NFYC; VEZF1; NACA; NR2F2; HOXC6; AFF1; MBD2; NKX3-1; PCGF2; ADNP; DDX54; HSBP1; RNF10; TRIM28; ELK3; HOXB7; ACTL6A; MAGED1; RERE; MYBL2; BRPF1; PLAGL1; HLTF; PLAGL2; EDF1; VGLL4; NCOA4; ENO1; ZBTB38; NCOA6; HMGN3; PHF20; NPAS2; CREBZF; HOXB2; EMX2; SUZ12; FOSL2; MITF; ZNF586; JUNB; DDX5; CEBPZ; CARHSP1; FOXD1; ETS2; SNAI2; ASCL1; SAP30; MAFB; NR3C1