Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09584 Brivanib GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 257 RRN3; PCGF2; CERS4; TERF2; BRCA1; NFE2; MED25; STAT5B; THAP10; MYBL2; NFE2L3; CIR1; ZNF219; TXNIP; IRF7; TBX21; BATF; TRIM24; PMF1; OLIG2; ZFPM2; HOXB6; TOX3; NFIX; CHD7; HHEX; AEBP1; ZNF24; AFF2; SUPT3H; SPI1; ZBTB18; REPIN1; PHF2; HOXB7; THAP7; NLK; ZNF215; SUPT4H1; PKNOX2; ASCL1; MAK; CEBPZ; MYB; ZNF263; PSMC3IP; KAT2B; HOXB5; PAX5; NR3C1; ZBTB39; ZNF292; APBB1; KLF2; MYT1; PIAS4; CEBPE; HIPK2; KLF11; CCNH; CCDC59; AIRE; ZNF711; MNDA; CBFA2T3; INSR; EMX1; SNAPC4; LHX2; SMARCE1; HLX; TTF1; ZBTB14; PRDM12; MAFF; CSDC2; RXRA; ZNF107; IKZF1; HBP1; ZNF423; ZNF195; ZNF688; PAX9; MTA2; SOX3; SOX2; HOXC4; SALL1; DOT1L; NR2F1; TSG101; ZNF117; SIX6; HDAC5; ERBB4; MYF6; ARID1A; MEIS2; TCEA2; KLF1; RARA; SOX12; DNMT1; THRA; NFE2L1; E2F5; BCOR; CEBPD; MYBL1; POU2AF1; GATA6; UBE2B; ZSCAN16; TCF7L2; BACH2; FOXF2; NR1H3; TGFB1I1; TAL1; ZBTB16; LHX1; TRIB3; CBX2; NR0B1; TBX5; PRDM10; ZNF770; NCOA3; CD3D; ARNTL; MNX1; RFX7; JAK2; CIITA; FOXA2; SOX13; ZNF394; ZNF391; SOX18; STAT5A; GTF2I; VAX2; DMTF1; SAFB2; BARX1; ZNF91; ZHX2; KLF15; AES; SPDEF; PPARG; TGIF2; SCRT1; TOPORS; TOX; SALL2; ZNF22; SIX3; TFEB; GATA2; TEF; HDAC4; ZKSCAN4; SOX5; WNT4; STAT2; TAF1A; MXI1; CHD4; GFI1B; PRDM1; ID3; HIC2; ZNF254; E2F8; NR1H2; ESRRG; ZIC3; NKX3-2; LEF1; CBX4; VENTX; TP73; JUP; ARNT2; REL; ZNF32; PRRX1; FOS; ZNF467; LHX3; SOX17; ZNF177; DDIT3; TCF12; POU6F2; JUN; CBX7; ZMYND8; BTG1; TCF21; NR4A2; PHIP; SRY; GFI1; FOXA1; PRDM2; ZNF124; L3MBTL1; SOX4; LMCD1; SOX21; ZNF710; HIPK1; POU5F1B; THRB; CREM; ING2; CTBP2; POU2F1; HOXD3; NEUROD1; CERS6; IRF6; ZIC1; LIN28A; TRIM22; MED1; PITX1; SOHLH2; ZNF273; CUX2; ID4; IRF8; ZNF202; ATF3; PRDM14; MED14; MEF2C; ZNF83; ID1; ZEB2; ZNF257; ST18; MYRF; SSX1; TBX3; HMGB2; ZNF331; DACH1; SPIB; TCF4; TFEC; CEBPA; ZNF589; WT1
Down-regulation 117 PARP1; TRIM29; ENO1; ERF; UBP1; WWTR1; HNRNPD; RNF14; ATF1; HIVEP2; WIZ; ZNF148; FOXC1; XRCC6; RBBP4; BBX; SFPQ; SMAD3; NUP62; CTNNB1; RAN; CBFB; HMGN3; ZNF410; SOX9; MEIS1; TCF25; CENPF; RBM14; ZBTB38; PUF60; RCOR1; RELA; TSC22D1; SNW1; MED15; NCOA4; BCL11B; SMARCA4; ISL1; CDYL; EGR3; TRIP6; ZFHX4; CCNC; YBX1; TSC22D2; TRIM28; MAGED1; C1QBP; BCLAF1; ARNTL2; HDAC1; SHOX2; RBBP7; ERBB2; EMX2; CREB5; CHD3; SMAD2; NPM1; FOXG1; DPF2; BHLHE40; SSRP1; ORC2; BRD8; PLAGL1; MTF2; MAF; ZBTB43; CBX6; DDX5; NFIB; NCOR2; HLTF; NONO; SNAI2; YBX3; DDX17; TRPS1; RBM39; FLNA; NACA; ACTL6A; ZSCAN18; HMBOX1; CBX5; ZNF146; MEF2A; MEOX1; NFAT5; PURA; NFKB1; ZNF468; EGR4; TAF10; TWIST1; MAFB; AGO2; BATF3; ZNF652; HSBP1; BAZ2B; IRX5; ZNF586; ZNF587; EYA1; ZNF264; NPAS2; RUNX3; PEG3; BMI1; AFF1; THAP11; HOXC6; MSX1