Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09583 Brivanib GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 287 NFKBIB; STAT5B; FOXO1; IRF4; TSG101; MYRF; NAB2; HOXC4; RARA; NFATC1; NFIX; HMBOX1; HOXC5; BATF; MED12; SCMH1; NFIC; NCOA2; LMX1B; HOXC8; IKZF1; ZBED4; HOXC10; PIR; EZH1; SHOX; TRRAP; ZSCAN18; CASZ1; RBPJL; STAT5A; ZNF768; ZNF671; CITED2; RAX; CD3D; HDAC3; CBX2; YEATS2; ATF6B; EWSR1; SPIB; SP140; EP300; GATA1; THAP3; MAFF; THRAP3; GATA4; SMARCD3; GBX1; HOXB1; KLF9; GCFC2; TOX4; ATF3; RNF141; SMARCE1; E4F1; CEBPD; AFF2; SNAI1; SAFB; SETDB1; AFF3; ZNF337; TWIST1; NKX2-5; ZNF419; MEOX1; GBX2; SAP18; ARNT2; CDC5L; FOXI1; HHEX; HIPK3; RFX1; TCEA1; TAF1; SNAI2; SMARCA2; RFX2; MBD1; GFI1; CCNE1; HIRA; STAT4; PRDM12; MXD1; ZNF467; CSDC2; ZFPM2; MAFG; TUB; REPIN1; TLX1; VDR; SSX3; ZNF654; RARB; CDX4; RERE; GTF3A; AEBP1; PRDM16; ZXDC; PCGF2; POU6F1; MNT; RNF6; PEG3; POU2F2; NFE2L3; COPS5; ADNP; BARX1; TCF7L1; NR0B1; VAX2; TBX10; TGIF1; RORC; KLF15; SP2; ACTL6B; FOXE1; SMAD6; URI1; SIX3; TFCP2; ID4; HIC2; DBP; TULP1; YBX2; GATA6; BACH2; POU2AF1; HOXC6; SMAD2; ZBTB16; MYT1; ATN1; ZNF12; FOXL2; ALX1; GTF2I; CIR1; PBX2; EN2; TLE2; JUP; ZNF22; CIITA; STAT2; SSX1; ELF4; NR1H3; TRIM22; NR2F6; YY1; PRKDC; HDAC9; KLF13; LHX3; ZBTB48; ZNF532; FOXN3; ING2; SERTAD2; NR1I3; ZNF211; NCOA6; CBFA2T3; ZIM2; BCL11A; MAGED1; TRIB3; OSR2; HDAC5; CERS4; ZNF215; SOHLH2; HAND1; PKNOX2; GLI2; RUNX3; ZNF304; ZBED2; NR3C2; HOXB6; LMCD1; MYCL; KLF6; TAF4B; MTDH; PRDM5; CHD4; WHSC1L1; FOXA2; ARID3B; THRB; ZNF32; WT1; ZHX2; ZNF217; ZBTB20; EN1; SRY; MDM2; MYBL1; FUBP1; ZBTB44; CTNNB1; OVOL1; KLF3; TBL1XR1; ZNF134; LIN28A; ZNF506; ZNF154; CITED1; SREBF1; HOXB2; HIPK2; ZNF611; JAK2; SALL2; RARG; CREB3L1; BNC2; SOX21; ZNF586; SOX3; TOX3; SMARCA1; PBX3; HMGB2; POU6F2; IL16; EGR3; SOX2; SOX13; CREBL2; HMGA2; SPDEF; FOXD1; HOXA1; HEY1; IRF9; EGR2; TCF7L2; NR4A3; TGIF2; ZNF257; ZNF117; HOXB7; TLE4; ZNF415; NR5A2; FLI1; ZNF160; ETV5; MEF2C; GRHL2; TCF7; TCF21; NANOG; BNC1; KDM5D; NFATC4; FOSB; ZNF587; LITAF; ZNF665; KAT2B; RFX5; FOXF2; ZIC1; EYA1; NEUROD1; LEF1; MYB; THAP11; IRF6; ZBTB18
Down-regulation 116 MEIS1; EMX2; ATF1; BASP1; RBBP5; ING3; MED21; RYBP; NUP62; YBX1; MED6; HDGF; CRK; E2F6; HMGA1; ISL1; CARM1; ZSCAN12; CRY1; BIRC2; TMF1; FLNA; TRIM29; NAB1; ZNF184; PAWR; BAZ2B; ZEB1; CDYL; TAF9; TGFB1; RELA; PATZ1; REST; MAZ; SMARCA4; YBX3; TRIM28; BLZF1; PCGF1; PMS1; BRIP1; CENPB; WWC1; DLX2; ORC2; ZFHX4; ZBTB38; SFPQ; ZNF430; NFYB; BAZ1A; DNAJC1; VEZF1; IFI16; BLM; SCAND1; MTF2; ZNF250; NFIB; SATB2; ATF7IP; NKX3-1; ARID5A; ZNF148; ESR1; ARNTL2; TTF1; PURA; FOSL2; MECOM; NPAT; KAT5; RUVBL2; PPARGC1A; USF2; ZNF468; FOXC1; KLF10; SPEN; ENO1; HOXA10; WWTR1; CREB1; ETS2; NPAS2; JUNB; SMAD7; SOX4; TCF12; TSC22D2; SUZ12; MAFB; CEBPB; ZNF266; TAF10; ZSCAN31; RAN; TRIP6; DACH1; ERG; ACTL6A; ID2; SUB1; ZNF302; FOXG1; BCL3; MSX1; HMGN3; CREM; TADA3; CEBPZ; ASCL1; ID3; NR2F2; NR3C1