Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09582 Brivanib GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 104 SP110; IRF7; BATF; TRIM22; HHEX; MYRF; RRN3; THRAP3; FOXN3; TAF9B; PMS1; ARRB1; SOX12; RSF1; TFAM; TSG101; IRF4; PBX2; BPTF; GTF2I; RNF138; RLF; ZBTB18; TWIST1; RXRA; CITED2; NKX2-1; SALL2; MEF2C; COPS5; SMAD3; MXI1; CEBPZ; STAT2; RARA; SAP18; MEIS2; NFIX; HMGB2; TOB1; TCEA1; HIPK2; CIITA; TOX; ZNF512B; ZBTB48; PEG3; ERBB4; STAT6; E2F8; SCAND1; FOXI1; GATA2; AHR; ZNF423; NLK; SPEN; ARNT2; PRRX1; ST18; IRF9; RBPMS; ZNF175; MNDA; GATA6; FLI1; LMCD1; MYCL; SPIB; HDAC9; RBBP8; PCGF2; GTF3A; FOXE1; ZFP36L1; NR0B1; ZEB2; TAF1A; ZFPM2; PLAGL1; ZNF467; FUBP1; WT1; HLF; SOX5; ZIC1; ZNF331; MAGED1; SOHLH2; E2F5; STAT1; ZBTB16; ZHX2; SAP30; TRIB3; CBFA2T3; SOX11; FOS; CUX2; KDM5D; LIN28A; NR4A2; PBX1; PBX3
Down-regulation 87 CRK; HOXC10; ZNF443; ZKSCAN1; TSC22D1; CLOCK; FOXC1; TAF9; MTA1; ZNF430; NKX3-1; PIR; ELF3; SIX1; PHIP; NR4A1; MYCN; ZNF148; LZTS1; PLAGL2; ENO1; TRIM28; ZNF12; NPAS2; TLE2; ZBTB20; WWP1; YWHAB; ZNF14; ZNF468; CUX1; TRIP4; TRIM29; WWTR1; ZNF189; RNF14; BCL11B; ACTL6A; ZNF134; ZBED1; ZNF160; RFX5; ZNF551; INSM1; TCEB2; ZNF136; RNF10; ATF7IP; ZNF140; SKI; CRY1; CIZ1; MSX1; ZBTB38; DDX5; BLM; ZNF587; ZEB1; NFIB; RNF4; SMAD1; ZNF586; SMARCC2; SHOX2; ZNF721; ZNF611; BATF3; HDAC1; HOXC6; CITED1; ZNF304; CBX3; HTATIP2; MEIS1; BMI1; RUNX3; LEF1; EGR2; HLTF; FOSB; NR2F2; FLNA; SOX9; ESR1; ASCL1; HES1; IRF6