Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09581 Brivanib GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 76 IKZF1; NFKB2; RLF; PNRC1; PTRF; GTF2F1; TFCP2; MKL1; NKRF; ZNF768; CTBP2; SCMH1; PITX1; HIPK3; CIITA; TRIM16; CBX5; TAF6; SREBF1; CEBPG; BCLAF1; GTF2I; CBX7; GATA6; FOXA1; TGFB1I1; CERS4; ZKSCAN1; MYRF; JAK2; JUP; CITED2; POU2AF1; BRD2; LMCD1; PAWR; SIM2; HIRA; STAT4; CARHSP1; NCOA2; MLXIP; WT1; ZNF160; LYL1; AR; AEBP1; PLAGL1; ATF4; ZFP36L1; PAX5; TRIP6; ARNT2; ZNF652; MNDA; MYBL1; FLI1; ZEB2; TOB1; TCEA1; SOX9; HIC2; ELF3; ZBTB16; STAT1; IRF9; IRF8; ZNF721; THAP11; MEF2C; HOXC6; TLE4; ZFPM2; ABL1; TXNIP; TFEC
Down-regulation 64 ATF1; ZEB1; STAT3; CCNE1; MYCBP; TAF9; ZIC1; NRIP1; TFDP2; CDYL; ATN1; ZHX3; AGO2; BLM; ZNF552; SMAD1; PDLIM1; DLX5; SNAI2; DNMT3B; ZNF468; JARID2; ACTL6A; RBBP8; ID3; ZNF134; ZNF211; ELK3; INSM1; TCF12; TGFB1; TCEB2; DEK; NKX2-2; OLIG2; VPS72; HEY1; ZFHX4; ZNF329; NFIB; IFI16; ID2; TFAP2A; SATB2; BCL11B; SERTAD2; ASCL1; SMAD2; ERG; KLF9; SATB1; EGR2; FOXG1; RUNX1; TSC22D1; KDM5D; ZNF586; ID1; TOX; TFAP2C; NANOG; PPARG; SSBP2; NR3C1