Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09580 Brivanib GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 95 IKZF1; MNAT1; SIX2; CHD8; TAF6; NFIC; CREB3L1; RORC; ZNF580; MED25; INSR; TCF7L1; CIITA; JAK2; HBP1; ATF4; LHX2; MED24; MYRF; PBX3; CEBPG; VDR; ARNTL2; RREB1; RARA; NFIB; CTBP1; ZMYND8; TRAK1; FOXM1; KLF5; SIX1; CERS4; MNDA; FOXO1; KDM5D; TFCP2; TBX19; SMARCD3; REPIN1; KAT2B; ZBTB16; LPIN2; CHD7; HOXB2; ZMIZ1; JUP; ELF4; DDIT3; TBL1X; FOXA2; SATB1; HOXC10; LHX3; HIPK1; IRF7; PRDM2; ARNT2; ZEB2; RXRA; HHEX; ZFP36L1; PLAGL1; ELF5; BCL3; PITX1; OVOL2; TRIP6; SOX9; STAT4; HIPK2; HEY1; YBX3; EHF; HIC2; TOB1; TXNIP; POU2AF1; PBX1; KLF3; NFATC4; PIR; LITAF; ZBTB18; MSX1; MYBL1; BCL11A; THAP11; ZNF91; MAFB; ARID5B; ABL1; TOX3; MEF2C; ZNF586
Down-regulation 48 MMS19; DNAJC1; ZBTB20; ING3; EGR4; PURA; ZBTB1; IFI16; ZNF248; LZTS1; BCLAF1; TBX3; BMI1; RBPMS; CREB1; BCL11B; NR1I2; ATF5; MBD2; MLLT10; NFKB1; ENO1; HMGA2; PROX1; CBFB; DNMT3B; ELK3; ZNF22; TLE2; DACH1; CHD9; NR4A2; MYCN; ID4; DDX5; AFF1; JUNB; MEIS1; EMX2; BAZ2B; ESR1; HES1; FOSB; CREM; TSC22D1; ZFP36L2; MYB; PPARG