Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09574 Cyt387 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 159 SOX2; PARP1; BATF; HOXA5; ZKSCAN1; TCEA2; ARID4A; THAP10; DMTF1; TAF4; TSC22D3; SREBF1; PATZ1; IRF4; NFE2L2; KMT2A; RSF1; ZEB2; MED6; ELF1; NFKBIB; SMAD3; TRIM16; KAT6B; STAT3; TGIF1; GATA2; PSPC1; VDR; CREG1; ZNF22; MYT1L; CBX6; BPTF; BAZ1A; SP110; JUP; NR2C1; ETV1; FOS; ZNF430; ARHGAP35; AIP; HHEX; EGR1; LPIN2; EHMT2; BRCA1; MNDA; RBBP4; PRMT2; TRIM22; POU2F2; MTA1; SIAH2; ID2; PIR; MYRF; TFEB; STAT2; CHD8; PQBP1; SALL1; GLI3; CBX5; IRF7; AHR; IRX5; HDAC5; PHF20; BRD8; KDM5D; ITGB3BP; FOXO1; TERF2; DBP; PMS1; CTNNB1; PRPF6; STAT5B; NFX1; AES; RBL2; RBBP7; PHF1; CBX7; ZNF281; LITAF; HMGB3; ZBTB16; SMARCA2; NR4A2; HLX; HMGB1; REPIN1; ERBB4; ZNF423; NR1H3; ZBTB1; TXNIP; STAT5A; NEDD8; RORA; KDM4C; HES1; POU2AF1; HLF; TBL1X; RBBP8; TCFL5; EYA2; PBX1; TCF4; IRF2; HOXB6; ZNF226; PCGF2; IKZF1; TOB1; GFI1; ZBTB18; NHLH2; TRIP6; HIPK2; LYL1; ZNF85; DDIT3; SPIB; ZFP36L1; PRRX1; TCF7L1; NR2F1; JAK2; HTATIP2; SPDEF; SALL2; ZNF652; SSX1; PAX6; NR0B1; CEBPZ; TWIST1; CREM; BTG1; SATB1; ZNF160; HOXB2; ZFPM2; ZNF721; ZNF467; ST18; PEG3; CUX2; ZIC1; RUNX1; ZNF331; KLF9; AFF1; TOX3
Down-regulation 187 LOXL2; NFKBIA; HOXB13; DLX2; PTRF; CNOT6; REST; MEOX2; MYC; WWTR1; SFPQ; C1QBP; ZBED4; ACTL6A; CNBP; HAND2; LMO1; WDR77; CBFA2T2; SATB2; YBX1; SUB1; ZSCAN5A; MYCL; ZEB1; SMAD1; BIRC2; BCL11B; ARNTL2; CCNC; ATF5; LZTS1; ZSCAN18; JARID2; HOXD9; POU3F2; ZNF134; PEX2; SMARCA4; PITX2; CBFB; ILF2; SRF; DAXX; INSM1; TRIP4; TAL1; FOXG1; MAZ; TDP2; TEAD3; KLF10; NPAS2; TEAD1; GATAD2A; JUND; CEBPG; ZNF813; UBTF; GFI1B; ZNF432; TRIM29; SOX11; HSBP1; RAN; ZNF468; IRX4; ZNF12; ZNF614; HOXC10; HOXD13; ABL1; HEY1; ATF3; MEOX1; SRCAP; NPAS1; HBP1; IRF1; MED17; MYNN; ZNF304; TRAF6; SMAD4; RNF10; PRDM13; TSC22D2; RBM39; CREB1; CDX2; TULP3; ZNF551; ZNF350; TCF21; RNF2; CCNT1; ZNF211; RXRG; ARID4B; KLF1; SIX2; CNOT2; SMARCC1; KLF4; ENY2; NFYA; ZFP69B; ID1; JUN; ZNF787; NR2E1; KLF7; CARM1; DR1; SKIL; DNAJC2; ISL1; PITX1; SOX15; NKX3-1; ELF5; HOXD11; WWP1; BHLHE41; EHF; ELF4; ZNF155; ZMIZ1; FOXF1; FOXA2; TFAP2C; KLF5; TCF12; CEBPB; SIM2; ZNF83; NR2F6; PREB; OVOL1; RFX5; SIX6; TFDP2; UTF1; CUX1; TLE4; HEY2; GLI2; ZNF586; HOXD3; ZNF266; NCOA4; IFI16; CSDE1; BATF3; BRD7; CITED1; NR2F2; ZNF606; ZNF426; NONO; SOX17; TRPS1; ATF4; MED1; MYF6; BNC1; JUNB; EN1; BMI1; DDX5; HIPK1; CALR; TOX; ID4; SUZ12; ZNF589; GATA6; MSX1; HDAC1; ID3; PBX3; SNAI2; NFATC3; ELF3; ZNF264; NFKB2; WT1