Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09568 As-601245 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 561 KDM5A; EHMT2; ETV1; RELB; CD3D; NFKBIB; EGR1; CRTC1; FOXJ1; ZNF205; HOXC5; HIVEP3; MZF1; DBP; SIX5; TGFB1; CEBPE; HDAC11; RAX; PBX2; FOXA2; LDB1; GBX1; HAND2; RSF1; PROP1; ZFHX2; NFAT5; ALX3; E2F4; ZBTB7B; TLX1; TONSL; PITX1; ZNF384; MNX1; RORA; CALCOCO1; ZNF768; ETV7; NFIC; TFAP4; ZNF580; RORC; MED25; TRIM24; ZSCAN2; ERCC2; HOXB3; HIF3A; ZNF629; PHF1; TBX21; FOXO4; NR0B2; CAMTA2; RHOA; CIC; TBX4; ZNF556; NKX2-5; PRDM1; CAMTA1; MBD3; TCEA2; SHOX2; POU3F2; HMBOX1; ZNF646; HNF1A; MTA2; ATF6B; NR2E1; ZNF816; ZSCAN32; TULP1; ZNF771; NOC2L; HEYL; CIITA; TEAD3; CRX; MYNN; LMX1B; KDM4C; NFIX; BARX1; SSX3; HDGF; ACTL6B; SREBF2; KLF15; PBXIP1; HMX1; LHX3; NKX6-1; NEUROG1; AR; SSBP3; NEUROD6; TLX2; HLX; MEIS2; ZKSCAN3; SPI1; GATA1; HSF4; KDM5C; MAK; ARID5A; TAF1; ZNF76; NR2F1; DYRK1B; PDX1; ZNF358; IKZF4; NPAS1; ARRB1; STAT4; PITX3; HOXB1; CASZ1; ZNF8; NRL; CDX1; HOXC8; SOX2; ZNF787; TCF15; SRCAP; TUB; MYOG; TAF6; MLXIPL; ZNF446; RFX1; FOXJ2; NKX2-1; RXRB; RING1; HDAC9; SLC2A4RG; FOXF1; RBPJL; ASCL3; ETV6; ZNF671; NHLH1; ZNF219; HOXD3; ASH1L; HOXA3; TAF6L; MLLT1; ZMIZ2; MEF2D; AIRE; LZTR1; EVX1; MED31; MAP3K10; ZNF813; LITAF; VSX1; SOX11; HOXC11; MYOD1; SMARCD1; THRA; ATN1; ATF7IP; PAX7; TBX10; ZNF180; HNF4A; APBB1; KMT2D; FOXF2; RBFOX2; ZNF606; RFX2; TEF; CREBL2; PAX6; NAB2; CEBPD; ESRRB; ONECUT1; TXNIP; ESR2; SIX6; CRYM; ZNF500; SATB2; FOXL1; HNF1B; ZNF223; AES; AFF2; PRDM8; ZBTB17; WNT4; CBX7; THRB; HOXC4; ZNF154; THAP10; SALL2; TRIM25; NEUROD2; FOXB1; ZNF22; CDX2; CHD2; TBX19; OVOL2; SKI; ZNF528; PRDM14; HOXD13; RBL2; ZNF274; HAND1; NR6A1; EP300; ZNF221; NR5A1; IRF3; ATOH1; ZNF835; ONECUT2; ZNF133; HIPK2; FOXP3; MXI1; FOXN1; ETV5; MAPK8IP1; CDIP1; ZNF536; PAX1; THAP3; MAML3; MYCN; HIC1; SCRT1; HMGA1; MYT1; LHX6; ZFP30; ZNF345; AFF3; FOXG1; DCC; GRIP1; IRF1; HOXB13; DMRT1; TFDP2; ZNF701; HOXB5; BRF2; ETV2; NR4A1; ZNF544; ZNF350; ZBTB43; SOX1; IKZF2; ALX4; ZNF211; PRDM9; ZNF324B; CBL; TBR1; DLX4; YBX2; FOXH1; PPARA; ING4; ZNF444; MKL1; ZNF75D; SSX7; HOXD1; TFEB; CDX4; SRY; CERS4; ZNF331; ETV3; POU6F1; ZBTB32; TP73; VENTX; MECP2; PRDM12; WHSC1L1; ZNF814; EYA3; ZKSCAN8; PRDM16; BCL11A; GSC2; LBX1; ZNF507; EPAS1; ARNTL2; ZNF549; ZNF184; HEY1; ZNF557; NR1I2; CALR; SIX3; ZNF225; BCL3; ALX1; HBP1; NOCT; HOXA4; NACA2; ATF7; CCNT1; FOXI1; ZNF696; MYF5; IRF5; IFNB1; IKZF3; HNF4G; HOXD11; ZBTB48; NFATC1; ZNF442; FEZF2; GTF3A; PEG3; HOXB2; NKX2-2; EMX1; BCL11B; ZNF286A; CREG1; TSHZ2; FOXD3; MED12; OVOL1; ZNF480; HDAC5; DLX2; SHOX; POU3F4; BARX2; TBX5; ZKSCAN7; ZNF253; ZIM2; POU6F2; SMAD5; STAT5A; SOX14; ZNF391; TBL1Y; SMARCA4; HOXB8; ZNF132; KLF1; GTF2I; STAT5B; ZNF287; RFX3; CARF; CBX2; ARID3B; ST18; ZNF688; ZNF155; PHOX2B; ZBTB7C; TFDP3; SOX5; GFI1; ZKSCAN4; TLX3; ZNF550; KLF12; GLI1; ZNF695; MYRF; ZNF34; ZNF41; HLF; ZNF239; HOXD12; NR0B1; ZNF93; NEUROD4; SOX21; ZFP37; SP4; BRDT; IRF8; ZNF467; ZNF85; IKZF1; ZNF407; FOXE3; MEOX2; MDM4; DLX5; LIN28A; CNBP; POU4F2; EZH1; ZNF43; TAF1C; ZNF235; NR4A3; ZFP2; PRDM2; SPIB; TULP2; HES2; ZNF749; IRF6; POU1F1; NR1H3; RARB; NFE2L3; NEUROG2; PRDM5; ZSCAN9; PIAS1; RERE; PKNOX2; ZNF532; ZNF423; HIPK3; ZIC3; PAX4; NR1H4; MDM2; NR1H2; ISL1; ZNF254; NKX3-2; PPARD; JUP; ZNF415; FOS; ZNF471; POU2F3; SOX18; ZNF117; BACH2; ZNF710; MED24; ZNF324; EYA1; SMARCA1; HESX1; RFX5; ZNF778; ZNF157; ZNF506; KLF9; RARG; CBX4; STAT2; TGIF2; GRHL2; MYCL; MAF; GATA6; ARNT2; TADA3; OLIG2; GCM2; ZNF264; EN2; ZNF674; ZNF74; TLE2; ZNF135; SUPT3H; ZNF175; ZNF124; SCAI; JAK2; ZSCAN18; TWIST1; NEUROD1; ZNF675; INSM1; VGLL1; ZBTB3; GATA2; ZNF257; ZBTB44; ZNF208; NR5A2; ZNF214; ZNF304; PRMT2; FHL5; HDAC4; MNDA; PBX1; ZNF682; POU2AF1; L3MBTL1; TCF7; ZNF669; E2F2; ZNF711; ZNF136; ZNF224; SOX3; ZSCAN31; RXRA; ZFPM2; FOXA1; TFAP2A; SOHLH2; ERBB4; ESR1; THAP11; SSX1; ZNF44; SSBP2; IRX5; YBX3; ZNF91; ASCL1; ZIC1; BRD4; TRIP6; NFATC4; CREM; ZNF141; TCF21; KAT2B; MSX1; EHF; NR1D2; CBFA2T3; ZNF589; SPDEF; ADRB2; TRIB3; NR4A2; FOSB; WT1; EN1; ZNF665; MEF2C; TBX2; TOX3; IKBKAP
Down-regulation 222 CCNA2; HOXA5; XBP1; CRK; FHL2; UBE2I; NUP62; USP22; ECD; TRIM29; SUV39H1; SNW1; NFKBIA; NFIL3; CDK2; PQBP1; BRCA1; TSC22D2; HOXA10; MBD2; PPRC1; SFPQ; PATZ1; CDK7; ZBTB11; KLF10; ATF1; TAF9; DNAJC2; KLF6; ITGB3BP; RB1; NRIP1; RBM14; FOSL1; SCAND1; REST; SP110; SMARCA5; BHLHE40; CCDC59; SMARCE1; BIRC2; MED6; NFYB; TOB1; FOXJ3; RBBP4; ADNP; APEX1; CHD1; VEZF1; CENPF; BCLAF1; ING2; SOX4; RREB1; CCNC; BCL10; TCERG1; RFC1; HNRNPD; IRF7; BASP1; NPM1; PAX8; SMAD1; SMAD3; ARNTL; RYBP; BAZ1A; PMS1; CTCF; UBE2B; PUF60; TBP; RBM39; RNF111; PKNOX1; RAN; PHIP; NR2F6; FOXO3; ZNF217; TAF12; CCNE1; ELF1; ERG; BTG1; SAP130; COPS5; CBX3; TBPL1; ILF2; TLE1; RLF; MGA; NRBF2; BRD3; MED17; E2F3; SUZ12; DEK; RNF138; TRIM27; ELK3; BLM; CTBP2; MED7; PSMC3IP; CHD8; TMF1; CTR9; BTAF1; ZNF146; TBL1XR1; SERTAD2; SIM2; DNAJC1; MYBL2; CBFB; CEBPG; RNF4; YWHAB; TRIM32; IFI16; AHR; HDAC2; ZNF12; NR2F2; ZBTB1; NKX3-1; NPAT; DMTF1; YAF2; MED13; SAP30; ENY2; SP100; NFE2L1; MNAT1; PAWR; PHF20; BCOR; TRIM22; SMARCC1; ZNF302; ZNF281; ZZZ3; NCOA6; THAP1; MLX; CRY1; TFAP2C; BLZF1; AATF; RUNX1; ZFP36L2; HMGB2; TSC22D3; PBX3; PURA; DDX5; DR1; ZMIZ1; SMARCC2; RBBP8; HOXA11; BRD7; ZNF84; KAT8; KMT2A; BACH1; KLF5; HOXC6; EED; PSPC1; PRPF6; ATF4; DACH1; ATF5; ZNF131; CTBP1; HOXA7; MITF; RARA; HIF1A; TAF1D; ID2; FOXC1; TLE4; HOXB7; KLF4; EDF1; TBX3; CREB1; BMI1; SMARCA2; KDM5D; TCF12; HSBP1; CEBPB; MAGED1; LMCD1; DNMT3B; STAT1; HOXA1; FUBP1; MED1; CUX1; ARID5B; AFF1; NPAS2; FOXO1; SMAD2; FLNA; MAFB; ZHX2; ZNF165; CEBPZ; NFATC3; ZNF586