Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09563	Linsitinib	GSE70138	HA1E	Human	24h	3.33uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	PPARD; IKZF1; SP110; PKNOX2; NFIX; UBE2L3; SOX9; MEF2C; SMARCB1; ZNF654; NCOR1; CTBP2; BATF; HIPK2; SP140L; MAFF; HIRA; CREB3L2; ASXL1; NR2E1; TERF2; LZTR1; MKL2; SIM2; NHLH1; FOXF2; ZNF131; GTF2I; CDC5L; ZSCAN31; SUPT3H; RAD21; MAX; FOXK2; EPAS1; ATF4; PRDM2; POU2AF1; RARG; ZNF688; JUP; PAX6; RBPJ; PEG3; SPDEF; FOXF1; SOX2; TGIF2; MYBL1; INSR; ZNF573; JAK2; HMGB2; SOX5; ZNF512B; TCF7L1; WWTR1; BCL11A; ZNF117; MYRF; SSX1; ZNF160; KDM5D; TRIB3; TCF7; E2F5; BRD4; TRPS1; HIC2; IRF8; CBFA2T3; ZNF665; TOX; AEBP1; ARNT2; EN1; NR2F2; MEIS2; WT1
Down-regulation	59	E2F6; MYCN; CCNE1; PATZ1; PIR; PREB; AES; HOXB6; TLE2; AFF1; TGIF1; BCL11B; HOXB7; ZNF586; BLM; ZNF329; AIP; MSX1; SMARCA2; ZNF134; ZNF468; EGR4; RNF10; ZNF551; MEOX2; NFYC; TSC22D1; ZNF410; PSMC3; BMI1; CRY1; GTF3A; ACTL6A; TBL1XR1; SMAD1; DPF2; ISL1; RFX5; EYA2; SMAD2; ZNF304; KLF11; ID1; DNMT3B; FOXD1; SOX17; HTATIP2; BAZ2B; MED1; ELK3; FLNA; ETS2; MEIS1; MECOM; BHLHE41; IKBKAP; HES1; HOXC6; NR3C1