Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09561 Ruxolitinib GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 236 ATN1; ZNF654; SALL2; PPARD; IKZF1; PROP1; PAXBP1; TGIF2; HIRA; LHX3; ELK4; FOXF2; RING1; RBFOX2; SOX2; USP21; RAD21; ZNF562; MAFF; ZNF232; ZNF688; ZNF580; KLF15; NHLH1; FOXA2; NR2C1; TUB; PRDM2; HHEX; NRL; AFF2; CNOT2; MYRF; SOX10; SSBP3; RARG; NEUROD2; NR2F6; TBX3; ZBED4; NKX2-1; ZNF552; MXI1; ZNF91; SUPT3H; SOX13; RBM39; ZNF816; CDYL; EP300; ZIC1; EZH1; MAK; NFIX; SPDEF; GATA1; TBX19; NR1H2; ZKSCAN3; ZNF444; LZTR1; ARID3B; PRDM10; AR; ZNF500; TP73; TGFB1I1; ZNF219; ZNF124; ZNF239; BNC2; CTNNB1; ZBTB16; ZNF215; HIPK1; TP63; INSR; PRRX1; THRB; ZZZ3; CAPN15; THRA; NFATC4; TCF7L2; ZNF131; SOX5; SIX3; ZNF692; NCOA3; AEBP1; ZNF33B; FOXH1; ZNF589; ZNF74; FOXE1; ZNF507; HOXB13; LIN28A; TAF1; HMBOX1; TFDP3; KLF13; CEBPD; ZFHX3; TRIB3; ZNF423; KLF11; NOCT; ZBED2; MED17; CBX2; ATF3; PRDM12; KLF7; FUBP1; PAX1; KLF3; CUX2; NFIC; KDM4C; POU5F1B; ZNF665; NANOG; PRDM14; ATOH1; ZBTB44; VENTX; SOX21; CBX4; SMARCD3; ERBB4; ZFPM2; TWIST1; TRPS1; BARX1; CBFA2T3; ZIC3; ARNT2; FOS; SIX6; NKX3-2; OVOL2; GATA2; JAK2; TBX1; HIPK2; RXRA; ZXDC; SSX7; ZNF710; ZNF778; FOXO1; ZKSCAN4; GLI2; KAT6B; DDIT3; ESR1; ZNF202; IRF6; NR1H3; ZNF93; PBX3; ZNF154; TAF5L; GRHL2; PRDM1; CD3D; SOX17; MNDA; PKNOX2; BACH2; TFAP2A; ZIM2; ZHX2; ZNF667; ZNF235; ZNF467; CHD2; ZNF331; HIC2; NCOA2; IRF9; SRY; TDP2; PBX1; EYA1; MYF6; ST18; ZEB1; SOX3; EN1; KAT2B; PEG3; HEY1; ID3; ZNF264; EPAS1; TAF1A; L3MBTL1; BCL11A; TFDP2; E2F5; TFAP2C; ZNF606; RORA; SNAI2; GFI1; HOXB2; ZNF415; HOXD1; HLF; TOX3; NR5A2; REL; VPS72; ZNF532; ZNF669; MYBL1; MYB; ZNF573; MEIS2; ZNF117; KLF9; ZFP36L1; MDM2; BNC1; STAT4; HOXB7; KDM5D; CALR; ZNF141; MEF2C; SMARCA1; KLF4; NEUROD1; ZBTB18
Down-regulation 70 RCOR1; FOXO4; XBP1; TSC22D2; SNW1; TBP; BAZ1B; ZMIZ1; NFYC; DNAJC1; SMAD3; SMARCA4; CENPF; DNAJC2; BMI1; MEIS1; NR2F2; RNF10; ELK3; FOXC1; NRIP1; KAT5; USF2; FLNA; ORC2; KLF10; HNRNPD; EMX2; NEDD8; STAT3; CTR9; RFX5; HOXC6; HLTF; NRBF2; SND1; FOXD1; DNMT3B; SUB1; PURA; TSC22D1; ZNF468; EGR3; YBX1; EDF1; YWHAB; AFF1; MBD2; BIRC2; SFPQ; BAZ1A; BHLHE40; HOXC10; RBPMS; SMAD2; HSBP1; TSC22D4; PTTG1; NCOA1; ETS2; CARHSP1; ZNF146; MAGED1; HMGN3; NFATC3; MAFB; STAT1; ELF3; ZBTB38; NR3C1