Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09560 Ruxolitinib GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 139 E2F2; IKZF1; CERS4; BCL11A; SMARCB1; GATA1; PAX5; HHEX; MEF2C; TGIF2; TERF2; PAX6; LYL1; GBX2; FOXO1; CIITA; SPI1; NCOA3; WHSC1; TXNIP; ATOH1; CBFA2T3; ONECUT2; HOXB1; LHX2; EGR3; INSR; CEBPG; ZNF91; AIRE; CAMTA1; HMGB3; MYCL; HOXD1; ZBED2; HOXD3; CAPN15; NRL; ZNF652; ZNF711; KLF11; TLX3; SNAPC4; GATA4; TP73; ZNF217; FEZF2; TAF9B; PNRC1; NEUROG2; PHF20; SOX2; SCRT1; CTBP1; FOXL2; HIC2; TEF; JAK2; PRDM2; HMBOX1; PLAGL1; SOX21; HAND1; PCGF3; TRIB3; NR1H2; L3MBTL1; ZBTB16; THRB; SRY; ELF4; ZSCAN9; ZNF165; ZNF264; RNF4; POU6F2; ZNF160; TCF7L2; RYBP; REL; LHX3; TWIST1; HIRA; ZNF611; ERBB4; NR0B1; SPDEF; BRCA2; ARNT2; ZNF573; ZKSCAN4; ZBTB20; KLF4; LIN28A; PRDM14; FLI1; CTBP2; ZMYND8; ARL2BP; JUP; ZFP36L1; ZNF669; BACH2; PEG3; SERTAD2; TRPS1; TDP2; KLF3; VGLL1; ZNF124; FUBP1; ZNF467; WT1; TFAP2A; MNDA; KLF2; ZNF721; BTG1; IRF7; FOXF2; CITED2; EMX2; ZNF665; SIX3; TCF4; ZIC3; ZNF117; OSR2; SPIB; ZNF544; ZHX2; AEBP1; ZFPM2; MYB; IRF8; ZNF589; TFAP2C; MEIS2; ZNF586
Down-regulation 42 CRY1; RBPMS; NRIP1; TAF7; BMI1; UBP1; ZMYND11; KLF12; HOXC10; ETV5; ELF3; NCOR2; NEDD8; ZMIZ1; ELK3; ENO1; TCF12; PCGF2; YWHAB; SMAD7; CTR9; BCL11B; FOXD1; DDX5; DNMT3B; SALL1; ZNF146; HOXB7; BCL3; MECOM; PIR; MEOX2; NKX3-1; ID4; HOXC6; NR2F2; ID1; CEBPZ; SATB1; NR3C1; DACH1; PPARG