Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09559	Ruxolitinib	GSE70138	HA1E	Human	24h	0.37uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	133	E2F2; IKZF1; ETV6; HOXB2; TRIP11; UBE2I; GCFC2; NFIC; ARRB1; WNT4; TWIST1; FOXA2; HOXB6; ZBED4; ID4; RORB; YAP1; FOXF2; MED12; TRIM22; LEF1; PCGF2; CALR; AFF2; GLI3; GATA6; ID3; NFIX; PIR; TAL1; ZEB1; ZBED1; MNDA; TOX3; CDK9; ZMIZ1; HOXB5; PEG3; SOX13; ZBTB16; RAD21; CAPN15; ZNF217; TBPL1; CREB3L1; MYRF; HIPK1; PGR; SMAD6; SOX17; PRPF6; SIX6; ATN1; IFI16; PRDM12; TBX19; POU2F3; ZNF688; ELF4; REPIN1; GFI1B; SOX5; RORA; ZNF710; ZNF423; FOXJ3; SMAD1; ZFP2; TCEA1; LPIN2; MXD1; OVOL2; HOXA2; HIRA; HLF; VGLL1; NR2F6; SALL2; GFI1; PRRX1; LIN28A; GRHL2; AEBP1; ID2; BRD4; PBX3; JAK2; CEBPD; ZNF512B; ZNF467; SIX3; ARNT2; INSR; MEIS2; IRF7; SOX4; EN1; KAT2B; ZFPM2; SOX2; MYB; ERBB4; ZNF415; IRF4; ZBTB18; SOX3; MYCL; PRDM2; HOXB7; VDR; E2F5; CUX2; NFATC4; DLX5; TCF7L2; ATF3; EHF; ZIC1; SPDEF; EGR2; ZIC3; SOX9; HIC2; TFAP2C; ASCL1; OSR2; PAX6; CEBPA; ZNF665; MSX1; TOX; TLE4; WT1
Down-regulation	77	PARP1; ING3; ABL1; SND1; TSC22D2; BASP1; FOXC1; TSC22D1; PFDN5; HSF2; FOXO3; KMT5A; PSMC3; ZNF3; BAZ2B; DNAJC1; CREB3L2; CREB1; HTATIP2; BAZ1B; RNF10; DMTF1; TMF1; DNAJC2; CCNT1; MED1; CUX1; ERBB2; DACH1; SMAD7; EDF1; ZMYM2; NAB1; YBX1; SIX1; ZNF468; ZBTB38; TCEB2; BBX; HMGB1; KLF10; TOPORS; ZNF419; BMI1; RYBP; CREM; TSC22D4; ELK3; PURA; MEIS1; TRIP6; HSBP1; SMARCA2; FLNA; STAT1; ZNF532; LMCD1; JUNB; PTTG1; YBX3; TADA3; CARHSP1; PAX5; ID1; TRIM28; ZNF551; NR1D2; LITAF; NR2F2; THAP11; KLF9; ENO1; GATA2; TXNIP; ZNF331; NR4A2; NR3C1