Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09557 Ruxolitinib GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 67 PSMD9; ETV1; NCOA3; BCLAF1; SIM2; ZBED4; HMGB2; ZKSCAN1; TAF9B; TTF1; NFIX; LEF1; ZBED1; ZNF195; FOXA1; TOPORS; MBD2; YBX1; ATF3; PFDN5; ARID4B; CTBP2; MYCL; EDF1; GRHL2; KLF6; GATA2; PITX1; RAN; NR1H3; SOX13; OSR2; PHIP; THRA; PRPF6; PCGF2; EHF; MITF; NR4A2; AEBP1; ZNF83; DDX5; ARNT2; BACH2; ZBTB20; MECOM; JAK2; CUX2; ZFP36L1; GATA6; FOXF1; IRF9; RFX5; HOXC6; ZNF532; YBX3; TOX3; ZSCAN18; TOB1; MNDA; SOX9; TFEC; IRF6; PBX3; THAP11; MYB; DACH1
Down-regulation 37 KLF10; CCNE1; MSC; KMT2B; ARNTL; DNMT3B; STAT3; BHLHE40; ASH2L; TGFB1; CREB3L2; SIX1; IRF2; ID1; ZNF146; TRIM22; ELF5; BCL11B; POU5F1B; HEY1; TCF7; CREB1; ZBTB38; JUNB; PLAGL1; RUNX1; BMI1; HTATIP2; HLF; SNAI2; ZNF91; ZNF117; NANOG; SATB1; SSBP2; ESR1; PPARG