Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID09556	Ruxolitinib	GSE70138	HA1E	Human	24h	10uM	EID0002

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	THAP10; SIX2; SFMBT1; SMARCB1; ZKSCAN1; IKZF1; SP140L; MED15; HOXB7; MXI1; IRF9; CALCOCO1; TRIB3; MEIS2; ITGB3BP; LEF1; HMG20B; SP100; AFF2; MYRF; ARID4B; NKX3-2; HOXA10; DDIT3; PPARG; NR4A2; TULP3; FOXF2; DBP; SSX1; TDRD3; SALL2; HOXA11; CBX5; FOXA1; ZNF160; KAT6B; PRPF6; ZNF32; ARNT2; FOXO1; ARID1A; ZNF721; MECP2; MECOM; SMARCD3; KAT2B; HIRA; EN2; RBL2; ZHX2; ZFPM2; TXNIP; CTBP2; CITED1; JAK2; NFAT5; ZBTB20; CBX7; SMARCC2; ZNF611; MITF; ZFP36L1; FOXF1; AEBP1; HEY1; PCGF2; BRD2; IL16; ST18; HIPK2; SALL1; HHEX; ZFP36L2; EYA1; ETV5; ERBB4; MNDA; ZNF423; TSC22D1; HIC2; ZBTB18; ATF3; ZNF652; EGR2; PAX6; KLF9; THAP11; SOX9; ZNF331; PEG3; ZNF264; PBX1; TLE4; NR2F2; IKBKAP
Down-regulation	55	KLF10; RNF14; DNMT3B; ETS2; BHLHE40; NCOR2; CNBP; DNAJC2; HSBP1; ORC2; NR2F6; TRIM29; ARNTL; RBM14; NFIB; ENO1; EGR4; ERG; AFF1; NRBF2; MAFG; NFIL3; SUB1; ELF5; CCDC59; BASP1; PAWR; ARNTL2; TSC22D2; MAF; IRX5; PPARD; MAFB; ATF4; FOXG1; RAN; PSMC3; FOXC1; RBPJ; ACTL6A; BCL11B; ELK3; WWTR1; SMAD2; NCOA4; TCF4; MEIS1; PLAGL1; TOX; CEBPB; FLNA; LIN28A; NANOG; DACH1; NR3C1