Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09555 Alpelisib GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 13 TBX2; ARID4B; EYA2; POU4F1; SIX1; MXI1; SMAD2; TBL1X; SOX9; NR2F2; ELK3; MED1; FLNA
Down-regulation 83 ZNF329; CREB1; ZSCAN31; TTF1; NKX2-2; SUPT3H; ZSCAN18; ZNF227; TWIST1; RYBP; PBX3; ZNF426; RBPMS; ZNF165; TRPS1; TFAP2C; LIN28A; NKX2-1; NR2F6; KLF11; NLK; INSM1; ZNF571; NANOG; SALL2; IRF8; MYCL; ZNF93; PLAGL1; CITED2; CUX2; ZNF544; MNDA; ID4; ZNF239; ZBTB20; TCF7L2; ZNF83; PAX6; ZNF394; ZNF43; IRF6; OLIG2; POU5F1B; PEG3; FOXA1; ZNF573; PBX1; ZNF117; KDM5D; HLF; ZIC3; ZNF232; ZNF532; MYB; TCF4; EGR2; ZNF415; SATB1; ZNF551; ZNF264; ZFP36L2; CBFA2T3; HIC2; GATA6; ZFP36L1; ZNF91; CEBPA; TOX; EN1; NEUROD1; ZNF665; ZNF423; TLE4; SPDEF; ZNF589; SSBP2; AEBP1; ST18; ERBB4; ZNF586; TOX3; PPARG