Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09554 Alpelisib GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 27 RSF1; MED13; SUPT4H1; BRIP1; YWHAB; ETV5; SP2; DEAF1; ELK3; BATF3; LPIN2; CARM1; BRD8; FLNA; ID2; SMARCD3; SUB1; ZBTB38; CREB1; MAGED1; MED1; ARID5B; HLTF; SOX9; NFATC3; ZBTB18; IKBKAP
Down-regulation 97 EHF; APEX1; SNAI2; NFATC1; ZNF33B; MBD2; PAXBP1; CEBPG; TRIM29; ISL1; NR4A1; MED21; JUP; HIC2; TAF5; PGR; ID3; HOXD1; NKX3-2; OSR2; DDIT3; ATF3; AEBP1; ZNF10; ZNF165; LYL1; PHIP; JUN; COPS2; ZNF44; ID1; TP63; HIRA; FOS; ARNT2; ZNF721; NRIP1; IRF6; LHX3; FOXF2; TCF7L2; ZNF273; TFAP2C; KLF4; ZNF532; KLF3; ZNF711; ZNF232; ZNF611; EN1; HHEX; ZNF160; SPDEF; HOXB6; ZFP36L2; ZSCAN18; TRIB3; HEY2; SOX2; HOXB2; HMGB3; ZNF587; ZNF141; ID4; REL; LEF1; ZNF91; CBFA2T3; SOX13; CEBPA; ETS2; ZNF652; SALL2; ESRRG; ZNF665; BACH2; INSM1; TBX3; NPAS2; LIN28A; TRPS1; ZIC3; SIX3; NR4A2; EYA1; GATA3; MYBL1; ZNF264; HEY1; TLE4; TOX3; TBX2; GATA2; SSBP2; ZNF586; MYB; PPARG