Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09553 Alpelisib GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 44 HOXA11; ARID4B; ZNF212; SMARCD2; HMGXB4; MED15; OSR2; DBP; EZH2; RHOA; EGR3; MEIS2; HOXA10; TRIM16; IFI16; HMG20B; EYA2; SPEN; NFAT5; MSX1; PRKDC; SMARCD3; TBL1X; SP2; SOX9; RXRA; JUND; ZFP36L1; IRF8; CEBPB; PLAGL1; BRD8; EGR2; YBX3; FOXO1; MEOX2; NR0B1; FLNA; ARID5B; MAFB; ABL1; IKBKAP; TLE4; PEG3
Down-regulation 57 CREB1; ING3; CERS6; CCNH; CEBPG; SFPQ; LYL1; KLF2; ID1; TULP4; TFDP1; HSBP1; RYBP; BANP; RAN; BCLAF1; ATF3; TDP2; URI1; ZNF302; ZNF165; FOS; TFDP2; ASCL1; SUPT3H; KLF3; MYCN; CBFA2T3; BRD2; MYB; NFATC4; ID3; ERG; KLF4; ZNF573; TOB1; ZNF91; THAP11; DACH1; HMGN3; IRX5; ZNF423; KAT2B; TFEC; NR4A2; LIN28A; ETS2; MECOM; HIC2; ZFPM2; AEBP1; ZNF665; PBX3; BTG1; ERBB4; TOX3; ZNF586