Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09552 Alpelisib GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 38 TBX2; CREB3L2; SP100; KLF10; MTF2; VEZF1; BATF; TGIF1; CHD1; PQBP1; FLNA; BAZ1A; MTDH; ELF1; NEDD8; HNRNPD; HMGB1; SMAD7; FOXC1; NPAT; ID2; TBL1X; BRD8; KDM5D; ZBTB38; ARID5B; MED13; HOXB7; YBX3; HDAC1; CITED2; NR1D2; ID3; HLTF; WWTR1; MAFB; AFF1; HOXC6
Down-regulation 89 PIAS4; THAP10; FOXA2; HOXB13; CEBPG; INSM1; IRF6; ISL1; TDP2; CTNNB1; MYCL; PIAS1; ZNF423; ZSCAN18; HIRA; SSBP3; SOX17; NR0B1; CUX2; MYCN; PLAG1; ZNF329; TCF7L2; EYA1; MYB; HDAC9; SALL2; MAF; OLIG2; TBX3; TRIB3; CRYM; AR; ARNT2; NR1H2; INSR; CBFA2T3; SOX11; TFEC; ZNF652; ZNF302; SSX1; ZIC3; SOX2; FOXA1; ZNF532; PPARG; ASCL1; BHLHE41; HEY1; JAK2; ZNF573; SPDEF; SIX3; GRHL2; NANOG; ZHX2; ZNF273; LIN28A; ZNF165; BCL11A; ST18; SMAD1; E2F8; ZIC1; AEBP1; TSC22D1; CREM; ZNF589; HIC2; THAP11; ZNF415; KLF3; PBX1; ESR1; TFAP2C; CTBP2; MEIS2; BNC1; KLF4; SAP30; ID4; TOX3; PBX3; DACH1; WT1; PEG3; SSBP2; ZNF586