Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09551 Alpelisib GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 36 KDM5B; TBX2; ETV5; HOXA11; CALCOCO1; ETV4; HOXA10; ARID4B; IRF2; BAZ1A; PCGF2; CREG1; BAZ2B; TLE2; FOXC1; HDAC4; CEBPB; NFIB; JARID2; RFX5; SOX4; ARID5B; BIRC2; SP3; NR2F2; SHOX2; CRYM; AFF1; MYBL1; FLNA; LEF1; TRIB3; CTBP2; IKBKAP; HOXC6; THAP11
Down-regulation 55 TRIM29; KLF6; SMARCB1; BHLHE40; GATAD2A; ZBTB43; YEATS4; ZSCAN18; KLF9; ZNF329; NR2F6; STAT3; RBBP8; ZSCAN31; ID1; ZNF165; RARA; IRF7; PEG3; INSM1; MXD1; SNAI2; REL; HOXD3; PDLIM1; JUNB; E2F5; HOXA1; TCF4; ZNF44; ZNF91; TAL1; TOX3; ID4; ZNF415; SSX1; SATB1; HIRA; ZNF264; ZNF423; KLF3; BHLHE41; HLF; ZNF665; ATF3; TCF7L2; NKX2-2; TOX; LIN28A; HIC2; AEBP1; ZNF586; SSBP2; WT1; PPARG