Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09549 Nvp-bez235 GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 238 TGFB1I1; SETDB1; ZNF629; ZBTB16; HBP1; RBFOX2; ZFHX2; MBD3; ZNF444; TCEA2; ZNF580; TBX2; ZNF688; SUPT3H; SREBF1; TAF6L; HEY2; TGIF2; MAFF; BATF; ZNF33B; ZFHX3; PFDN5; POLR3C; LDB1; BPTF; FOXF2; ZNF32; SOX2; ZNF133; CBFA2T2; ZNF219; VAX2; NRL; RING1; FOXN3; PPARD; GBX1; NR2C1; CEBPD; SOX10; HHEX; ZNF22; PROP1; ZNF593; ZNF500; PRDM12; ZNF239; CNOT2; GCFC2; LHX2; LZTR1; MZF1; HEYL; NFIC; NEUROG1; L3MBTL1; KAT6B; MED12; ING4; ZFPM2; HOXC4; ZNF24; DDIT3; SALL2; ATN1; ZNF816; ZNF667; ZNF835; TAF1; CERS4; ZNF91; TULP3; HIPK2; HINFP; PRDM2; ZSCAN9; HDAC5; NEUROD2; ZIC1; KLF15; SOX5; TFAP2A; TLE2; ARNT2; KAT8; LHX3; ZNF512B; KAT2A; NHLH1; TCF3; EP300; MYRF; SOX13; CCNH; KLF13; MTA1; NFATC4; NOCT; GTF2IRD1; RARG; NCOA2; EZH1; HOXB5; ZNF654; SPDEF; CAMTA1; NR0B2; SOX3; HDAC4; ZNF423; BACH2; NR1I3; DBP; EPAS1; STAT4; VENTX; RBL2; RORA; NFIX; THRB; TULP1; NEUROD6; CEBPB; TEF; SIX6; NR2E1; TRIB3; CTBP1; IRF1; CDC5L; MLLT10; ZKSCAN4; TCEA1; CD3D; NR0B1; KLF3; CREBL2; FOXO1; BCL6; NKX3-2; NR1I2; MXI1; ZNF74; MECOM; CUX2; ZNF232; TFDP2; ST18; VPS72; TP73; ZNF467; RXRA; DEK; TCFL5; CHD2; NR2F6; THRA; PRDM14; AHR; ZBED1; TAL1; GLI2; EN1; FOXG1; ZNF177; HOXB6; NR1H3; POU6F2; KLF11; SIX3; PRPF6; SPIB; SOX9; PRMT2; SOX11; HIRA; ERBB4; PLAG1; ZNF264; NANOG; ID4; PROX1; TGIF1; ZFP36L1; ZNF135; FOXE1; CEBPA; ZHX2; FEZF2; HOXB2; GFI1; ZNF345; ZNF711; ZNF334; TCF7L2; BNC2; OVOL2; PAX6; ZNF606; HMGB2; INSR; MEIS2; PEG3; FLI1; SOX17; TBL1X; MED14; TOX; KAT2B; NEUROD1; PBX1; EYA2; ZNF93; IRF9; TRPS1; HOXB7; ATF3; PRRX1; JAK2; MYBL1; HLF; PBX3; ZNF589; IKZF1; ZIC3; ZNF141; LITAF; IRF6; ZNF665; AEBP1; ID1; ZNF415; ZBED2; BTG1; SOHLH2; WT1; ESR1
Down-regulation 80 XBP1; MYCBP; TSC22D2; GTF2A2; BCLAF1; SUB1; CBFB; MAGED1; SFPQ; EGR3; NFIL3; ENO1; YWHAB; CCNE1; ZNF468; EGR1; UBP1; BAZ1A; SMARCA5; CRYM; BMI1; TBPL1; RCOR1; ATF7IP; DMTF1; IRX5; RHOA; NRIP1; HNRNPD; DNMT3B; RBM14; PURA; FOXC1; RNF6; AFF1; BAZ1B; NRBF2; HOXC6; KLF10; MED1; RUNX1; ZMYM2; IRF8; HOXC10; PIAS3; ACTL6A; FOXJ3; YBX1; ING2; ISL1; NKX3-1; SATB2; TGFB1; ZBTB38; TSC22D1; BBX; CBX3; JUNB; RBPMS; ZEB2; ETS2; ZNF146; PIR; HDAC1; ELK3; NR2F2; ZNF532; SMAD2; CREB1; FLNA; SNAI2; HTATIP2; MAF; TCF4; CEBPZ; HLTF; ASCL1; NFATC3; TOX3; NR3C1