Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09548 Nvp-bez235 GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 132 HBP1; SIRT2; KLF5; KLF13; TDP2; ZNF91; FOXN3; HR; TCF25; ZEB1; HOXB5; APEX1; PQBP1; MZF1; CDX1; MAFF; NR2C1; DDIT3; ZNF276; TAF6L; RB1; CDYL; SMARCB1; ZNF268; GATA1; MED12; SUPT3H; ZNF33B; ZIC1; EZH1; PPP1R13L; ZNF219; PPARD; HMGA1; TCEA2; HOXB2; HDAC9; TRPS1; DBP; HOXB1; KLF1; ZNF544; KAT2A; DLX5; ZSCAN9; TRIM29; MLXIPL; KLF6; NFIC; TFAP2A; NR1H2; KDM5D; ZNF175; ZNF211; HOXD1; ZNF84; POLR3C; ZNF224; INSM1; TFDP2; DEAF1; POU5F1B; ZNF195; ZSCAN18; CNBP; CEBPD; SREBF1; ZNF131; COPS2; OVOL1; ZNF83; ZBTB16; DEK; ATOH1; ARNT2; LYL1; CREBL2; SPDEF; ZNF665; PRDM14; ZNF239; HOXB6; ZNF667; FOXF2; ZNF426; TRIM22; SOX2; CEBPA; CTBP2; ZNF430; JUP; TCEA1; ZNF264; TRIB3; PAWR; ZNF611; HDAC5; INSR; BNC2; SOX9; KLF3; ATF4; WWTR1; YBX3; ZIC3; ZNF532; ST18; TWIST1; ID1; STAT4; PAX6; ZNF423; TAL1; TCF7L2; HOXB7; ZNF160; OSR2; MYRF; ZNF117; ZNF165; NKX2-2; ELF3; SIX3; HIRA; AEBP1; TOX; KLF9; IRF6; LIN28A; ZNF586; ID3; NANOG
Down-regulation 70 XBP1; MYCBP; GTF2A2; MAGED1; NFKBIA; BAZ1A; ELF1; UBP1; TBPL1; SMAD7; NFIL3; PATZ1; ELK3; NRIP1; SFPQ; POU2AF1; IRF2; TSC22D2; BMI1; YWHAB; HOXC10; CHD3; SUB1; POLR2A; HMGN3; SMARCA5; ZEB2; BAZ1B; PAX8; CTR9; VEZF1; PHOX2B; SMARCA2; SLC2A4RG; TRIM32; ING2; CREBZF; MBD2; ZNF107; RFX5; PLAGL2; IRX5; SSX1; SP3; STAT6; HNRNPD; LEF1; CALR; HOXC6; RBPMS; NR3C2; MSX1; BBX; CREB1; AFF1; THAP11; SERTAD2; HLTF; NCOA1; IRF4; KLF2; JUNB; TLE4; SOX11; ENO1; CEBPZ; TXNIP; NR2F2; TBX2; SATB1