Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09547 Nvp-bez235 GSE70138 HA1E Human 24h 0.37uM EID0002
Types Number Response transcription factors
Up-regulation 85 HBP1; HDAC6; HMGA1; FOXN3; MXI1; DDIT3; PQBP1; CDK7; APEX1; TCF25; ZZZ3; TDP2; ZNF32; ING3; ATF4; NR2C1; HOXB5; ING4; GTF2IRD1; MTF2; SMAD3; CALCOCO1; TGFB1I1; ZNF219; FOXO4; BTF3; ARNT2; PFDN5; DEK; MTA1; EZH1; ZKSCAN1; CEBPB; HOXB6; CIZ1; COPS2; ZNF223; BRD8; LPIN2; ZNF623; CREBL2; POLR3C; CIR1; ZNF224; TRIB3; ZNF91; TGIF1; ZNF232; GTF3A; KDM5D; FOXG1; HOXB7; ZFP36L1; ZNF83; ZNF667; HOXD1; TCEA1; SCAI; TSC22D1; ZBTB16; MYBL1; ST18; CTBP2; BTG1; STAT4; SALL2; FOXF2; ATF3; YBX3; CARHSP1; TCF7; INSM1; KLF11; ZFPM2; ZIC3; MAFB; TRIP6; TOX; SOX9; ZNF264; ZNF423; THAP11; NR4A2; NFATC3; ZNF586
Down-regulation 53 MYCBP; XBP1; NFKBIA; GTF2A2; BHLHE40; CCNE1; FOSL2; PIAS2; SUB1; SFPQ; PAX8; SMARCA5; HOXA10; SIAH2; MYCN; STAT3; CTNNB1; SMAD5; YWHAB; NFIL3; PTRF; RBM14; TSC22D2; SMAD7; TCF4; MAGED1; PIAS3; ELF5; IRX5; CREB3L2; BMI1; BAZ1A; ENO1; SERTAD2; CALR; ELK3; RUNX1; AFF1; DNMT3B; FOXC1; ZEB2; SMAD1; HLTF; LEF1; SNAI2; TBX3; MYB; MEIS2; ASCL1; SATB1; ESR1; DACH1; WT1