Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09546 Nvp-bez235 GSE70138 HA1E Human 24h 1.11uM EID0002
Types Number Response transcription factors
Up-regulation 80 HDAC6; HBP1; NR2C1; MNT; DDIT3; TCF25; APEX1; SETDB1; ZNF32; FOXN3; CALCOCO1; ZNF268; TCEA2; ZNF593; BRCA1; SUPT4H1; SOX9; FOXO4; RXRA; PQBP1; MED12; IRF1; DAXX; ZNF140; ZNF219; CIZ1; MAFF; ATF4; TRIP6; ING4; SP140L; ZNF688; ETV4; MTA1; ZNF131; EZH1; PAWR; ID4; TBX21; KLF11; TRIB3; ARID1A; ZNF266; ZNF224; HOXD1; ETV5; CBX7; HMGA2; AEBP1; TDP2; ZNF91; POLR3C; DEK; CTBP2; ZNF430; CREBL2; JAK2; INSR; MYRF; IRF9; ARNT2; ZFPM2; BATF3; MED13; HDAC9; EGR3; TRIM22; YBX3; SALL2; ZNF544; NR0B1; SOX13; JUP; MAFB; KDM5D; BTG1; IRF8; ZBTB18; ERBB4; ZNF586
Down-regulation 71 HOXA5; MYCBP; GTF2A2; NFKBIA; XBP1; BHLHE40; SMAD7; SMARCA5; RBM14; NFIL3; STAT3; MEIS1; PITX1; BAZ1A; YWHAB; ELK3; ELF1; SMARCA1; SFPQ; CCNH; HOXA10; NLK; BCLAF1; SUB1; MTDH; TBX3; PAX8; ATF5; PHOX2B; NFKB1; BMI1; PLAGL2; MAGED1; MBD2; ZFHX4; EYA2; SMARCA2; SIAH2; YBX1; TRIM32; SMAD1; BBX; JUN; ZEB2; NFIB; LEF1; SPIB; AHR; MAF; ISL1; HLTF; HEY1; EMX2; AFF1; SATB1; CALR; SATB2; HSBP1; PLAGL1; BASP1; SOX11; KLF9; MEIS2; TCF4; ESRRG; ID1; FOXF1; TLE4; PPARG; PEG3; SSBP2