Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09545 Nvp-bez235 GSE70138 HA1E Human 24h 3.33uM EID0002
Types Number Response transcription factors
Up-regulation 81 HMGA1; BRCA1; VGLL4; SMAD3; DDIT3; SIX2; NPM1; BTF3; NR2C1; GTF2IRD1; KLF5; DBP; APEX1; TRIM29; ATF4; MNT; HBP1; FOSL1; CNBP; PHF1; SSBP2; CARHSP1; MTA1; PFDN5; ZNF23; FOXO4; FOXC1; ARNTL2; ZNF84; COPS2; ZNF33B; KAT5; CEBPB; THAP10; YBX1; SOX9; SMARCC1; PHF20; BANP; FOXN3; DEAF1; ZNF302; TCF7; TOB1; ZNF83; TCF12; FOXG1; PNRC1; NONO; TDP2; SIM2; FOXD1; IRX5; BRD8; ITGB3BP; ZNF160; INSM1; NR2F1; HDAC4; HEY1; KLF6; DEK; RFX5; ZIC1; DACH1; HOXD1; NPAS2; YBX3; HDAC1; MYC; ELF3; ID1; ZNF611; HDAC9; TRIP6; MSX1; NR1D2; INSR; ARNT2; PBX3; AEBP1
Down-regulation 59 MYCBP; RUVBL1; XBP1; CCNA2; CREB3L2; RNF6; CALR; GATAD2A; YWHAB; NFIL3; PAX8; PTRF; TCF4; CREB1; SMAD1; UBP1; VDR; CITED2; BHLHE40; MED17; TBL1XR1; NLK; MAGED1; HOXA10; BIRC2; SSX1; THAP11; PITX2; HIC2; SMAD7; IRF4; STAT1; MLXIP; SUB1; SIAH2; HHEX; GATA6; ZEB2; ZBED2; NR5A2; ZBTB20; TLE4; YEATS2; CUX1; TSC22D1; SPIB; ZBTB18; BNC2; TFEC; HIRA; IRF9; FOXO1; TRIB3; IKZF1; WT1; GATA2; TOX3; MYB; PEG3