Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09544 Nvp-bez235 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 92 HDAC6; ADRB2; BRCA1; HBP1; HMGA1; FOXO4; NFE2L1; DDIT3; HR; NR2C1; DBP; APEX1; ATF4; KLF13; ZNF33B; PSMC3IP; ZNF408; TCEA2; ING3; FOXN3; BTF3; SIX2; ZZZ3; TAF7; MNT; CIZ1; ZNF84; TERF2; MTA1; FOXC1; TCEB2; MED12; EZH1; ZNF175; ZNF574; PHIP; PNRC1; HOXB7; ZNF536; FOXD1; KAT7; BRD3; CBFA2T2; KLF2; SMARCC2; CREG1; TSC22D1; MXI1; MAZ; FOXJ3; CEBPB; DLX2; CREBL2; PPARG; DEAF1; NCOR2; TAF10; PURA; TOB1; RNF138; SUPT3H; AHR; THRA; HTATIP2; BTG1; NR1D2; PAX5; BRD8; KLF11; HDAC4; RUNX3; NONO; ZNF551; NR2F2; KLF4; TCF12; TADA3; BAZ2B; ZNF302; YBX3; NKX3-1; HOXC6; FOXF2; ZSCAN18; PSIP1; MYRF; INSR; MAFB; ST18; NFATC3; TOX3; ZNF586
Down-regulation 76 MYCBP; XBP1; RUVBL1; LOXL2; NFKBIA; GTF2A2; CCNA2; CCNE1; MED4; RNF6; ABT1; VDR; PAX8; ILF2; BHLHE40; YAP1; NFYA; NFIL3; RCOR1; EYA2; CALR; SFPQ; ZFP36L1; BAZ1A; PTRF; SMARCA5; WWP1; PITX2; ELF1; ZBED2; PITX1; MECOM; LZTS1; ID4; FOSL2; CTNNB1; FOXO1; CREB3L2; SOX17; CITED1; TSC22D2; HIPK1; SUB1; ZNF654; MEIS2; PBX1; WT1; SMAD1; IRF4; TRPS1; NR5A2; TCF4; MAGED1; ESR1; ELK3; HIC2; CTR9; PRRX1; ZNF44; HIRA; SMARCA1; E2F8; RUNX1; PEG3; LEF1; MEIS1; IFI16; ENO1; EGR2; SNAI2; E2F5; MSX1; LITAF; GATA6; SATB1; ERBB4