Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09509 Plx-4720 GSE70138 HA1E Human 24h 10uM EID0002
Types Number Response transcription factors
Up-regulation 74 HDAC6; STAT5B; ZNF133; ZNF205; TAF6; BAZ1B; ID2; ARID4B; MLXIPL; SMARCD2; SPEN; ZNF24; TRRAP; RBFOX2; TEAD3; ZIC1; EMX2; ZNF692; RING1; TRIP6; SHOX2; RFXANK; ARID1A; TGFB1I1; HOXA11; MYRF; FOSL1; CEBPG; TCF12; SOX11; ZKSCAN1; EZH2; SIAH2; GFI1; KLF13; TSC22D4; MEIS2; FOS; GLI2; ZBTB20; BATF3; ACTL6A; SOX9; SMAD7; ZNF22; TBL1X; KAT6A; ATF4; CD3D; EYA2; RXRA; TRIM16; TRIM28; JUND; SMARCD3; TWIST1; ELF5; HIPK2; MYC; CREB1; GATA6; PAX6; POU2AF1; KLF9; ARID5B; ZFP36L1; MED1; TRIB3; CITED2; FOXG1; ABL1; ID4; MSX1; IKBKAP
Down-regulation 70 EGR1; BRCA1; TFDP1; UBE2B; SFPQ; RB1; TERF2; TBPL1; ELF1; RREB1; PQBP1; USP22; ZNF217; RFX5; SP100; ZNF721; MYCN; ENY2; HSBP1; CCNH; STAT3; IRF7; DNMT3B; HMGB3; TBL1XR1; ERG; ZMYM2; KLF2; KLF6; HOXA1; NPAS2; SIM2; SREBF1; ZNF165; TGIF2; MAF; TCFL5; IRX5; ELK3; MITF; AGO2; HMGN3; CCNC; LMCD1; AFF1; PBX3; TLE1; SPIB; AHR; PAX5; FOXC1; SAP30; ZNF160; CEBPA; TSC22D1; HOXD1; CREM; TXNIP; TFAP2C; HTATIP2; THAP11; TOX3; TFEC; ZBTB18; NR4A2; HOXC6; ZNF331; WT1; MYB; NR3C1