Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09508 Pf-477736 GSE70138 HA1E Human 24h 0.04uM EID0002
Types Number Response transcription factors
Up-regulation 360 STAT5B; NFE2; ZNF629; USP21; PARP1; STAT5A; ZNF274; GLI2; SETDB1; NFATC1; FOS; SREBF1; POLR3C; GATA1; PHF2; PPRC1; ATF6B; CD3D; IL16; ZNF22; MXD1; UBTF; KLF1; NKRF; GFI1B; TDRD3; SSX1; CDX1; NCOA3; CCNA2; IFNB1; VAX2; LMX1B; NFYA; CITED1; ZNF467; HDAC6; ZKSCAN8; ZNF85; ZNF529; ZBTB14; NR4A3; ASH1L; TTF1; PGR; LYL1; PPARD; PML; ZNF33B; MZF1; SHOX; NFIX; NR1H3; SAP18; FOXI1; ZBED4; TLX3; MEOX1; TAF1; SSBP3; NKX3-2; MYRF; REPIN1; GTF2IRD1; FLI1; ZNF226; MLLT10; MDM2; MBD1; CDX2; BCL10; NR2C2; FOXA2; SSX7; ZBTB3; KDM4C; PIAS2; ZNF536; PPARA; GTF2I; KDM5D; IRF4; TAF4B; SNAI1; RNF6; ZKSCAN7; TBR1; MDM4; ZNF8; CEBPG; ZSCAN18; HMGB2; THAP1; ST18; SIX3; SNIP1; CARF; ZNF460; THRB; ZNF688; SRY; ZNF10; HIPK2; ASCL2; SATB2; ZFPM2; PKNOX1; TOX; CBX2; FOXN2; AFF3; AFF4; EHMT2; SIX1; ZNF131; BATF; EYA2; EGR2; THRA; TAF5; KLF13; AR; ZNF175; HDAC5; ALX4; HSF4; MYT1L; RARG; GATA6; ZNF223; EMX1; HESX1; SCRT1; CREG1; BCL6; ARRB1; PAX9; GRHL2; GFI1; POU2AF1; CERS6; MXI1; NEUROD6; TFEC; NKX3-1; ID4; TXNIP; TEF; RAD21; ELF4; CBFA2T3; EGR4; TULP2; AIP; POU3F1; RUNX2; RBBP8; ZNF480; ATF7; YEATS4; MYCL; ASXL1; OVOL2; ZFHX3; ZNF710; SIAH2; TAL1; CBX8; ZKSCAN4; CDC5L; NCOR1; ZNF12; TFAM; FOXE1; POU1F1; CUX2; ZNF132; PBXIP1; PRDM5; SREBF2; AGO2; ZNF749; SP4; TMF1; POU6F1; TBX5; ZNF780B; ZNF343; RLF; CCDC59; ZNF443; JAK2; SOX5; NR1I2; TRIM16; ZNF142; POU4F2; TBX19; PAX4; IRF6; STAT2; HOXB8; EMX2; BCOR; ING2; ZNF214; ZNF221; ZNF571; ZNF117; SMAD1; PIAS3; MYB; ZNF423; PTRF; AEBP1; PRRX2; SOX14; STAT4; HIRA; BHLHE41; OVOL1; NLK; ZNF695; ZNF507; ZNF248; SNAPC4; IKZF1; SOX3; WT1; ZNF549; KAT7; POU6F2; ZFY; ZNF43; ZNF391; DR1; TFDP2; ZNF273; CHD2; ZNF394; RBL2; ZNF580; BRDT; ZNF345; SOX21; ZNF34; ZNF324; ARID1A; ZNF442; ZNF135; DACH1; DCC; ZNF141; HIPK3; BNC2; PCGF2; FOXF1; RFX2; SIX6; ATOH1; MBD2; ZNF550; HMG20A; PRRX1; IKZF2; NEUROG2; TOPORS; WHSC1L1; ZNF254; ZNF287; VPS72; MYF6; ZNF814; MEF2C; PAX6; ZIC1; GCM2; CDK8; TFCP2; CREM; NR2E1; ZBTB1; OLIG2; PRMT2; TCF7L1; MED20; ZNF506; DNMT3B; ZNF208; ZNF81; FEZF2; LIMD1; E2F5; ZNF362; TCFL5; HLX; KLF3; ERBB4; MEF2A; KLF5; ZNF225; ZBTB44; ZFP69B; ZNF329; SOX9; ZIC3; ZNF124; NHLH2; ZNF606; CREB3L1; FOXG1; BARX1; EN2; PROX1; HDAC4; PRDM14; CHD7; SAP30; NEUROD1; ZNF682; SALL2; NR3C2; ZBTB25; NKX2-2; CTBP2; RUNX3; ZNF532; HHEX; EYA1; MNDA; ZNF573; OSR2; HDAC9; ZNF711; ZNF165; SPDEF; TCF4; ZNF544; ZNF415; IRX5; INSM1; NANOG; ESRRG; SOHLH2; ZBED2; TRIB3; BNC1; GATA3; ADRB2; SOX11; NR4A2; IRF8; ASCL1; TRPS1; TOX3; ZHX2; LIN28A; KLF4; ZNF665; SSBP2
Down-regulation 136 CNOT6; BRCA1; HDAC3; IRF1; SF1; ZNF593; SP110; FLNA; XRCC6; CHD1; ZNF432; NOC2L; KDM5C; CERS4; MBD3; LEF1; HIF1A; SUZ12; PSMC3; ZBTB40; TBL1XR1; TSC22D2; PURA; CREBZF; HIVEP2; ELK4; KDM2A; MTF2; NR2F2; DLX2; SP100; WHSC1; SUPT4H1; ENO1; PSMC3IP; CHD9; HBP1; CENPF; BCL3; HMGA1; PPARGC1A; BRD8; NEDD8; FOXM1; CBX3; MEF2D; GABPB1; MED13; SIM1; TRIM29; DAXX; KLF2; CNBP; NPM1; CEBPB; NONO; MDFI; IFI16; CBFB; HNRNPD; ZNF468; FOXD1; CARHSP1; GATAD2A; RBM39; TULP3; ZNF512B; BATF3; ATF4; CARM1; TFAP2C; CTBP1; RUNX1; PTTG1; HMGB3; MEIS1; SFPQ; TCF20; TP63; SMARCA2; ACTL6A; STAT1; BHLHE40; CREB3L2; ID1; UBE2B; TGFB1; KAT2B; BASP1; FOXJ3; CALR; TSC22D4; ZNF281; HIPK1; CTR9; FOXL2; NR2F6; ZNF586; HOXC6; HOXA10; NFYC; EDF1; YEATS2; ZNF430; TAF1A; ISL1; ZMYND8; SOX4; JARID2; RORA; ZFP36L1; SCAND1; THAP11; NFATC3; HOXB6; HSBP1; FOXC1; ZEB1; MED1; BRD4; MAGED1; FOXO1; PBX3; NCOA1; CUX1; WWTR1; LPIN2; TRIM28; CREB1; CEBPZ; HTATIP2; FOSB; BTG1; ZNF160; AFF1; NR3C1