Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID09507 Pf-477736 GSE70138 HA1E Human 24h 0.12uM EID0002
Types Number Response transcription factors
Up-regulation 391 PKNOX2; HMBOX1; MYRF; PEG3; RSF1; SOX10; SOX13; PGR; NR0B1; ST18; MECP2; ADRB2; AFF2; E4F1; SOX5; RBFOX2; HOXC5; SCMH1; HEY2; OLIG2; SREBF1; DNMT1; AR; TGS1; AEBP1; TFAP4; SOX2; CHD8; ZNF529; MAML1; POLR3C; CEBPD; JUN; ZNF556; VAX2; PNRC1; CERS4; ATN1; ZIC1; NR2F6; NR1I3; RFX7; ARID1A; ZNF345; LHX2; GMNN; SKI; RING1; TGFB1I1; STAT5A; SALL2; BACH2; TEAD3; SSBP3; NCOR1; ID4; SUPT3H; EYA2; ALX3; EN2; ZNF536; CITED1; ZIM2; SIN3B; TAF5L; ZNF711; HEY1; YAP1; TCEA2; ZNF467; JAK2; AIP; TAF1; EMX1; SPDEF; NHLH2; MKL2; TOPORS; ZBED1; HMGXB3; NEUROD1; PRDM10; GLI3; CERS6; LEF1; ZKSCAN4; ZNF589; ZNF136; MYT1; PRPF6; CLOCK; SOX3; NKX3-2; MNX1; ZNF337; SUPT7L; WT1; ARL2BP; PLAG1; HOXA1; CBX2; CUX2; GLI2; THRA; ZNF507; NKX2-2; ASH1L; TRAF6; CITED2; RUNX2; ZNF117; ETV1; RARB; CARF; SOX12; MDM4; ZNF286A; ZNF223; TFEC; MEF2A; HOXC11; ZKSCAN8; BNC2; CHD2; EGR2; PRDM2; PAX9; MBD4; SOX21; HDAC5; KLF4; TTF2; IRF9; ZNF695; RCOR3; AFF3; ZNF324; KLF2; HOXC10; ZBTB44; ZNF492; PEX2; NEUROD2; LZTR1; IFNB1; PPARD; ZNF696; HIRA; ZNF500; ATF3; POU6F2; HOXD1; SMARCD3; ZNF257; ZNF34; ZNF254; ATF7; RFX3; NR2C2; FOXO1; HOXD13; TLE2; WHSC1L1; ZNF362; POU6F1; ZNF771; MYBL1; IKZF2; ING4; AFF4; ASCL3; TAF1C; GRIP1; GATA4; BCL6; FOXF2; EZH1; TFCP2; HIVEP1; ELF2; RORB; ZSCAN16; FOXI1; CBFA2T3; THRB; TCF4; TP73; RARA; CDX2; HOXC4; POU3F1; NRL; BNC1; CHD3; LHX3; IL16; ZNF814; ZKSCAN7; GCM1; ZNF74; ZNF141; RARG; ZNF236; SHOX; ZNF675; NEUROD6; ZFHX3; MED14; ZFP37; MED17; ZNF764; TCFL5; NCOA2; ZNF132; ZNF460; FOSB; PBX1; NR2E1; JUP; ZNF225; ZBTB3; ZNF10; PRMT2; ZKSCAN3; TBR1; GRHL2; TULP2; PRDM9; AHR; ZNF654; TRIM16; TRPS1; ZNF135; STAT4; TOX3; HOXD3; ZNF682; MLLT10; TDP2; ZBTB16; ZNF33B; SOX18; IRF4; ETV3; SP4; ZNF273; ZIC4; ZNF334; ZNF287; DCC; ZNF692; TULP1; HIPK2; CBX7; PAX4; ZNF214; FEZF2; SKIL; FLI1; HMGB2; SRY; ZNF780B; NR6A1; NFIX; JUND; NCOR2; PBXIP1; ZNF710; ZNF623; ERBB4; TAF4B; E2F5; ZNF407; SSBP2; SPIB; TBX5; BARX1; ZNF165; ZNF688; GCM2; ZBED2; SOX30; PRRX1; ZNF391; EN1; ARID3A; FOXE3; CIR1; TCF7L2; SOX15; NR2F1; ZNF81; ZNF423; TAF9B; CREBL2; ZNF224; HLX; NANOG; ZNF701; HOXA2; POU2F3; REL; ZNF85; SSX7; ZEB2; ZNF22; IKZF3; ZNF669; HOXD11; CDIP1; NR5A2; NR0B2; POU1F1; BCL11A; PRDM14; RBPMS; ZNF667; POU2F1; SIX6; ZNF80; TXNIP; HIC2; E2F8; TAF1A; BRD4; ZNF154; SIX3; ZNF253; L3MBTL1; ZNF506; MEIS2; BRCA2; TSC22D1; ZNF208; LZTS1; ZNF235; TCF21; PROX1; PAX6; CREM; IRF8; MDM2; ESRRG; RBL2; ZSCAN31; ZFP36L1; ZNF440; ZNF493; SP3; SOX11; NR1H3; ZNF512B; KLF3; THAP11; NFATC4; HDAC9; FHL5; ZFP69B; CEBPA; SSX1; SOHLH2; VGLL1; IRF6; ZBTB18; MYB; ZNF124; NR4A2; TLE4; ZNF652; HLF; ZNF232; ZNF532; MEF2C; ZHX2; HOXB2; KLF9; INSM1; ZNF415; FOXG1; KAT2B; ZIC3; CREB1; ZNF160; INSR; IKZF1; CHD7; TFAP2C; ZNF665; GATA6; ZNF264; ZFPM2
Down-regulation 126 HMG20B; BASP1; VEZF1; HOXA5; ATF1; MAX; NFKBIA; EMX2; ATF4; ACTL6A; NFIB; AFF1; SNW1; CBX3; ZNF468; HSBP1; ZBTB38; XBP1; MTF2; KLF5; XRCC6; HMGB1; SUZ12; ZNF281; FOSL1; BCL3; RBBP4; RAN; BRD3; ENO1; PBRM1; SND1; HDGF; BAZ1B; NUP62; CARM1; NRBF2; HLTF; DNAJC2; SUPT4H1; BRPF1; MYCBP; ZNF593; NR1D2; HBP1; RNF4; ZNF24; TRIM28; NPM1; RUVBL2; IRF1; HMGA1; DNMT3B; TADA3; TSC22D2; HOXA10; HNRNPD; HTATIP2; SF1; TERF2; PSMC3; TRIM29; ORC2; KLF10; MED1; MXD4; ZMYM2; PDLIM1; CBFB; GTF3A; CNBP; TAF10; REPIN1; MED24; LPIN2; CEBPB; NELFB; MSX1; BHLHE40; ZNF140; NFE2L1; EDF1; MAFG; TGIF1; ZNF134; NCOA4; TBL1XR1; CTR9; RHOA; BBX; HDAC1; SMAD2; DDX5; CNOT3; SFPQ; ELK3; MED13; FLNA; SCAND1; DEAF1; TERF1; SIX1; TRIM32; JARID2; SUB1; BAZ1A; TGFB1; CSDE1; ZNF302; FOXC1; BMI1; ZNF146; NONO; TSC22D4; ELF5; BRD8; NFATC3; ETS2; SMARCA1; MAFB; ZNF586; NR2F2; DACH1; ID1; HOXC6; ID3